LINC00515

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LINC00515 is a long intergenic noncoding RNA [1].

Annotated Information

Name

Approved symbol:LINC00515

Approved name:long intergenic non-protein coding RNA 515

HGNC ID:HGNC:16019

Previous name:chromosome 21 open reading frame 71

Alias symbol:PRED21

RefSeq ID:NR_024092

pubmed_id:31140829

prev_symbol :C21orf71

Characteristics

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Function

LINC00515 downregulation was correlated with platinum resistance and relapse-free survival (RFS) of HGSOC (p < 0.05)[1].

Regulation

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Expression

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Diseases

high-grade serous ovarian cancer (HGSOC)[1]

Labs working on this lncRNA

  • Zhejiang Cancer Research Institute, Zhejiang Cancer Hospital, Hangzhou, Zhejiang, PR China.[1]
  • Key Laboratory Diagnosis & Treatment Technology on Thoracic Oncology of Zhejiang Province, Hangzhou, Zhejiang, PR China.[1]
  • Center for Medicinal Resources Research, Zhejiang Academy of Traditional Chinese Medicine, Hangzhou, Zhejiang, PR China.[1]
  • Department of Gynecologic Oncology, Zhejiang Cancer Hospital, Hangzhou, Zhejiang, PR China.[1]
  • Laboratory Medicine, Zhejiang Cancer Hospital, Hangzhou, Zhejiang, PR China.[1]
  • Key Laboratory of Head & Neck Cancer Translational Research of Zhejiang Province, Hangzhou, Zhejiang, PR China.[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Ni MW, Zhou J, Zhang YL, Zhou GM, Zhang SJ, Feng JG, Xu Q, Zhou Y, Mou HZ, Zheng ZG. Downregulation of LINC00515 in high-grade serous ovarian cancer and its relationship with platinum resistance. Biomark Med. 2019 May;13(7):535-543. doi: 10.2217/bmm-2018-0382. Epub 2019 May 29. PMID: 31140829.