PSMB8-AS1
The aberrant expression of PSMB8-AS1 is highly relevant to glioma tumorigenesis and prognosis of GBM patients.[1]
Contents
Annotated Information
Name
Approved symbol:PSMB8-AS1
Approved name:PSMB8 antisense RNA 1 (head to head)
HGNC ID HGNC:39758
Previous name:TAP1 and PSMB8 antisense RNA 1
Alias symbol:XXbac-BPG246D15.8|TAP1-AS1
RefSeq ID:NR_037173
LncBook ID:HSALNG0049455
Prev_symbol:TAPSAR1
Characteristics
PSMB8-AS1 mainly located in cytoplasm of glioblastoma cells, indicating post-transcriptional regulation.[1]
Function
PSMB8-AS1 regulating GBM cell proliferation, apoptosis and radioresistance . overexpression of PSMB8-AS1 promoted the level of DDIT4 through inhibiting miR-22-3p.[1]
Regulation
LncRNA PSMB8-AS1 acts as miR-22-3p sponge to mediate DDIT4 expression and regulate glioblastoma progression.[1]
Expression
High expression trends of lncRNA PSMB8-AS1 was observed in both glioblastoma tissues and cells. [1]
Diseases
Glioblastoma (GBM)[1]
Labs working on this lncRNA
- Department of Neurosurgery, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, 030012, China.[1]
- Department of Neurosurgery, Heze Municipal Hospital, Heze, Shandong, 274033, China.[1]
- Department of Neurosurgery, Affiliated Hospital of Jining Medical University, Jining, Shandong, 272029, China. Electronic address: hanguangkui1997@163.com.[1]
References
[1](1)
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