UVRAG-DT
UVRAG-DT, UVRAG divergent transcript, is a novel diagnostic biomarker for postmenopausal osteoporosis (PMOP).
Contents
Annotated Information
Name
Approved symbol:UVRAG-DT
Approved name:UVRAG divergent transcript
HGNC ID:53952
Alias symbol:LOC100506113
RefSeq ID:NR_144531
Characteristics
UVRAG-DT is a two exon transcript of 689 bp that is found on human chromosome 11q13.5 [1].
Function
Downregulation of UVRAG-DT may be a prognostic factor for postmenopausal osteoporosis patients [1].
UVRAG-DT and LOC105374771 may be involved in pathogenesis of postmenopausal osteoporosis (PMOP) by regulating the expression of diacylglycerol O-acyltransferase 2 and LGALSL, respectively [1].
Regulation
NA
Diseases
- Postmenopausal osteoporosis (PMOP) [1]
Expression
UVRAG-DT is downregulated in postmenopausal osteoporosis (PMOP) [1]
Labs working on this lncRNA
- Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P.R. China. [1]
References
Sequence
>gi|392973718|ref|NR_144531.1| Homo sapiens UVRAG divergent transcript (UVRAG-DT), long non-coding RNA
000081 CGCTTGTCTG CCTTGGCAGG CCCCTTGTGC AGTCTTTTCC CGGCGTGAGC GTGCAGGGAT TGAAAAGGAA TGCTTTATGG 000160
000161 TTCAGCAGAG AGCCACCACG CAGGATGCAC TGGGACCTGA GAACCGTCGG GCAGTCCCAC GAGCTCTTTC ATGACCAGCT 000240
000241 CCAACCGACA AGTACACGCC CCTTCGCACT CCACTAGCTA GTAAGCTGAG CTACAAGGTG TGCCAGGCAC CCAGGACGCC 000320
000321 GATTCACCGC TTCAGTGAAG GCCCAGCTCA AATGCCACCT CTTCCATGAA GACTTCCGTG ATCCACAATG ATAGCATCTC 000400
000401 CAGCAATTGC TTCTATAATG AATAGCATGA GTCATTCTGC AGGATGTTGA TCTTCCTTTT TTTACTCCTA GACTGAATTT 000480
000481 TTCCACCACC TGGATGAACA TAGCAGAAAG AACATAGTGT TTTAGAGTCA GACACAATAG GAATCAGGCA CTTTGGAATC 000560
000561 TTGGCTCTAC CACCTTTGAG CTATGTATCC CAAGGCAAGT CACTTCCCCT CTCTCAGCTT TAAAATAGTA ATAGGATTGC 000640
000641 TGTAGGGATT AAAGTAAATC AACATATGTA AAGTGCCCAC ACAAAAAAA