TMEM18-DT
Long-noncoding RNA TMEM18-DT, located 247 bp upstream of the TMEM18 gene, play integral roles in metabolic processes, including adipocyte differentiation and glycometabolism.[1]
Contents
Annotated Information
Name
Approved symbol：TMEM18-DT
Approved name：TMEM18 divergent transcript
HGNC ID：54481
Alias symbol：AC092159.2
RefSeq ID：XR_001739245
Characteristics
location:2p25.3
Function
TMEM18-DT plays integral roles in metabolic processes.[1]
Regulation
TMEM18-DT may be an important regulator of TMEM18, which is an important susceptibility gene related to obesity and type 2 diabetes.[1]
Expression
SNPs inTMEM18-DT may contribute to GDM by affecting TMEM18 expression.[1]
Disease
Gestational Diabetes Mellitus[1]
Labs working on this lncRNA=
- Emergency Department, First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China.[1]
- Department of Obstetrics, People's Hospital of Rizhao, Rizhao, China.[1]
- Nanjing Maternity and Child Health Care Institute, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.[1]
- Department of MICU, Women's Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital, Nanjing, China.[1]
- Department of Neonatology, Wuxi Children's Hospital Affiliated to Nanjing Medical University, Wuxi, China.[1]
- Nursing Department, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.[1]
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 Hu D, Miao W, Chen T, Xie K, Shi A, Zhang L, Li R, Wen J. Genetic Variants in AC092159.2 and Risk of Gestational Diabetes Mellitus in a Chinese Population. DNA Cell Biol. 2019 Oct;38(10):1069-1077. doi: 10.1089/dna.2019.4827. Epub 2019 Jul 30. PMID: 31361511.
