TP73-AS2
TP73-AS2 revealed differentially expressed in early-stage esophageal squamous cell carcinoma and benign esophagitis.[1]
Contents
Annotated Information
Name
Approved symbol：TP73-AS2
Approved name：TP73 antisense RNA 2
HGNC ID：40591
Alias symbol：RP5-1092A11.2
Characteristics
location:1p36.32[1]
Function
TP73-AS2 promoted cell proliferation in esophageal squamous cell carcinoma cells.[1]
Exosomal TP73-AS2 promoted cell proliferation in esophageal squamous cell carcinoma cells.[1]
Regulation
TP73-AS2 binds to cancer-associated proteins[1]
Expression
TP73-AS2 is highly expressed in ESCC-derived exosomes, ESCC cells and tumor tissues.[1]
Disease
Early-stage esophageal squamous cell carcinoma (ESCC) and benign esophagitis. [1]
Labs working on this lncRNA=
- School of Public Health, Guangdong Key Laboratory for Genome Stability & Disease Prevention, Carson Cancer Center, Shenzhen University Health Science Center, Shenzhen 518060, PR China.[1]
- Department of Thoracic Surgery, Shenzhen People's Hospital, Shenzhen 518020, PR China.[1]
- Department of Hepatobiliary Surgery, Shenzhen University General Hospital, Shenzhen 518060, PR China.[1]
- Department of Digestive Endoscopy, The First Affiliated Hospital of Shenzhen University, Shenzhen 518023, PR China.[1]
- Department of Thoracic Surgery, The First Affiliated Hospital of Shenzhen University, Shenzhen 518023, PR China.[1]
- Department of Biostatistics, Nanjing Medical University, Nanjing 211166, PR China.[1]
- Department of Environmental Health, Harvard TH Chan School of Public Health, Boston, MA 02115, USA.[1]
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 Tian L, Yang L, Zheng W, Hu Y, Ding P, Wang Z, Zheng D, Fu L, Chen B, Xiao T, Wang Y, Chen F, Liu J, Gao K, Shen S, Zhai R. RNA sequencing of exosomes revealed differentially expressed long noncoding RNAs in early-stage esophageal squamous cell carcinoma and benign esophagitis. Epigenomics. 2020 Mar;12(6):525-541. doi: 10.2217/epi-2019-0371. Epub 2020 Feb 11. PMID: 32043367.
