Lnc-NDST1-1:2

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Annotated Information

Transcriptomic Nomeclature

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Function

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Regulation

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Expression

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Allelic Information and Variation

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Evolution

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Labs working on this lncRNA

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References

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Basic Information

Transcript ID	lnc-NDST1-1:2
Source	LNCipedia2.1
Same with	,
Classification	antisense
Length	256 nt
Genomic location	chr5+:149829002..149829258
Exon number	1
Exons	149829002..149829258
Genome context
Sequence	000001 GCCGTATTGC GGGGCCGAGG CCTTAAAAGG CTGGACCCGC ACTCACCCTT ACTTCACAAG CTCCTCCCTG AAAGCAAAAC 000080 000081 GGGCCTTCTG AGACCAGGAA CGAACTCAAT CCCGAGTTGG CCAGGATCCA GGTGGGCCAG CCGCGCGTCT CTTGCCCGGC 000160 000161 ACCTAGCTCG GTTCCCACGG AAAGACCCCC GTCTCTCGTC CCAAGCCCCA CAGGGTCCCC TCGCCGCAGG ATGCCCCCCG 000240 000241 ATTGTCGCGC CCGGGC

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Annotation (From lncRNAdb)

[Lnc-NDST1-1:2]

Section	Description
ID	Alpha 250/ Alpha 280
Characteristics	Two overlapping antisense RNAs from intron 1 of the human ribosomal protein 14 (Rps14) gene, identified by RNase Protection Assay (RPA).. RPA expression analysis using both cell extracts and cell-free transcription system indicates full-length sizes of 250 and 280 nt, respectively. Transcripts terminate at the same nucleotide, therefore alpha-250 overlaps alpha-280 along its whole length.. Transcription of both RNAs is resistant to high concentrations of RNAPII inhibitor alpha-amanitin.
Expression	Ubiquitously expressed in the human tissues and cell lines examined. . Alpha-250 was almost exclusively cytoplasmic. Alpha- 280 was mostly in the nucleus.
Function	Regulates RPS14 transcription.. Each lncRNA can interact with the Rps14 gene loci to stimulate its expression in-trans.. Each lncRNA is transcribed through a known enhancer with putative transcription factor binding abilities, suggesting the 'enhancer' may be the transcribed RNA, which could be recruiting transcription factors to the Rps14 gene.

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