CCAT1-L
Contents
Annotation
Name
CCAT1-L
Alias
NA
Disease
Disease: colorectal cancer (PMID:24662484)
Dysfunction type: NA
Description: CCAT1-L plays a role in MYC transcriptional regulation and promotes long-range chromatin looping. Importantly, the CCAT1-L locus is located within a strong super-enhancer and is spatially close to MYC. Knockdown of CCAT1-L reduced long-range interactions between the MYC promoter and its enhancers. In addition, CCAT1-L interacts with CTCF and modulates chromatin conformation at these loop regions.
Function
Function Mechanism: transcriptional regulation (PMID:24662484)
Biological Process: pathogenic process
Description: NA
