CCAT8

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Annotation

Name

CCAT8

Alias

NA

Disease

Disease: colorectal cancer (PMID:25663692)

Dysfunction type: expression

Description: Of the seletced lncRNAs, four lncRNAs named CCAT3, CCAT4, CCAT5, and CCAT6 (also named MYCLo-2) are upregulated in CRC cell lines, and two lncRNAs named CCAT7 and CCAT8 are downregulated in CRC cell lines. MYC-regulated lncRNAs, named MYCLos. The MYC-regulated MYCLos may function in cell proliferation and cell cycle by regulating MYC target genes such as CDKN1A (p21) and CDKN2B (p15), suggesting new regulatory mechanisms of MYC-repressed target genes through lncRNAs.


Function

Function Mechanism: NA (PMID:25663692)

Biological Process: pathogenic process

Description: NA