LY86-AS1

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LY86-AS1 is an differentially expressed gender-associated lncRNAs in human AD brains.[1]

Annotated Information

Name

Approved symbol:LY86-AS1

Approved name:LY86 antisense RNA 1

HGNC ID:HGNC:26593

Previous name:LY86 antisense RNA (non-protein coding)|LY86 antisense RNA 1 (non-protein coding)

Alias symbol:FLJ33708

RefSeq ID:NR_026970

Prev_symbol:LY86AS|LY86-AS

Characteristics

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Function

The pathways involved in neurodegenerative diseases, synaptic vesicle cycle, and endocytosis were overly represented within gender-associated lncRNA-correlating genes. [1]

Regulation

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Expression

The expressions of gender-associated LY86-AS1 is negatively correlated with Braak stage of AD.[1]

Diseases

Alzheimer's disease (AD)[1]

Labs working on this lncRNA

  • Core Laboratory, School of Medicine, Sichuan Provincial People's Hospital Affiliated to University of Electronic Science and Technology of China, Chengdu, People's Republic of China.[1]
  • Department of Computer Science and Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA.[1]
  • Key Laboratory of Biological Resource and Ecological Environment of Chinese Education Ministry, College of Life Sciences, Sichuan University, Chengdu, People's Republic of China. Electronic address: zj804@163.com.[1]
  • Department of Computer Science and Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA. Electronic address: jcui@unl.edu.[1]
  • Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, USA. Electronic address: guoku.hu@unmc.edu.[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Cao M, Li H, Zhao J, Cui J, Hu G. Identification of age- and gender-associated long noncoding RNAs in the human brain with Alzheimer's disease. Neurobiol Aging. 2019 Sep;81:116-126. doi: 10.1016/j.neurobiolaging.2019.05.023.