Lnc-DILC
Contents
Annotation
Name
lnc-DILC
Alias
NA
Disease
Disease: liver cancer (PMID:26812074)
Dysfunction type: interaction
Description: Depletion of lnc-DILC markedly enhanced LCSC expansion and facilitated HCC initiation and progression, whereas ectopic expression of lnc-DILC dramatically inhibited LCSC expansion. Mechanistically, lnc-DILC inhibited the autocrine IL-6/STAT3 signaling.Moreover, our data suggested that lnc-DILC mediated the crosstalk between TNF-α/NF-κB signaling and IL-6/STAT3 cascade.
Function
Function Mechanism: transcriptional regulation (PMID:26812074)
Biological Process: pathogenic process
Description: biomarker
