POU3F3
Contents
Annotation
Name
POU3F3
Alias
NA
Disease
Disease: esophageal squamous cell cancer (PMID:24631494)
Dysfunction type: NA
Description: Levels of a lincRNA encoded by a gene located next to POU3F3 (linc-POU3F3) were significantly higher in ESCC than neighboring nontumor tissues. In RNA immunoprecipitation assays, linc-POU3F3 was associated with the EZH2 messenger RNA (mRNA). Overexpression of linc-POU3F3 in cell lines increased their proliferation and ability to form colonies, and reduced the expression of POU3F3 mRNA, whereas knockdown of linc-POU3F3 increased the levels of POU3F3 mRNA.
Function
Function Mechanism: transcriptional regulation (PMID:25445282)
Biological Process: pathogenic process
Description: NA
