FOXD2-AS1
Contents
Annotated Information
LncRNA FOXD2-AS was highly expressed in NSCLC tumors [1].
File:FOXD2-AS1 regulates Wnt/b-catenin signaling in NSCLC cells.jpg
FOXD2-AS1 regulates Wnt/b-catenin signaling in NSCLC cells [1].
Approved Symbol
FOXD2-AS1 (FOXD2 antisense RNA 1 (head to head))
Synonyms
MGC12982
Chromosome
1p33
RefSeq(supplied by NCBI)
NR_026878
pubmed IDs
28132805
Disease
Lung cancer
Function
Loss- and gain-function assays suggested that FOXD2-AS1 remarkably modulates the tumorigenesis of NSCLC through Wnt/β-catenin signaling.[1] FOXD2-AS1 overexpression promotes NSCLC progression.[1]
Expression
lncRNA FOXD2-AS1 had significantly high expression in NSCLC tissues.[1].To be specific, high expression of lncRNA FOXD2-AS1 was shown in 23 cases of 45 (53.3%), in which unchanged was revealed in 10 cases (22%) and down-regulation in 12 cases (24%) [1]
| Experiment | Forward primer | Reverse primer |
|---|---|---|
| qRT-PCR | 5'-TGGACCTAGCTGCAGCTCCA- 3' | 5'-AGTTGAAGGTGCACACACTG- 3'[1] |
Labs working on this lncRNA
- Department of Thoracic Surgery, The Second People's Hospital of Liaocheng, Liaocheng, Shandong 252600, China.
- Department of Thoracic Surgery, The Second People's Hospital of Liaocheng, Liaocheng, Shandong 252600, China. Electronic address: wchqba@163.com.
