Difference between revisions of "HCCAT5"

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(Created page with "==Annotated Information== ===Approved Symbol=== HCCAT5 ===Approved Name=== hepatocellular carcinoma associated transcript 5 (non-protein coding) ===Previous Symbols=== _ ===Sy...")
 
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===Approved Name===
 
===Approved Name===
 
hepatocellular carcinoma associated transcript 5 (non-protein coding)
 
hepatocellular carcinoma associated transcript 5 (non-protein coding)
===Previous Symbols===
 
_
 
 
===Synonyms===
 
===Synonyms===
 
HTA, FJ222407
 
HTA, FJ222407
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===pubmed IDs===
 
===pubmed IDs===
 
20130911, 23314567
 
20130911, 23314567
 +
 +
===Functions===
 +
HTA could play important roles in Hepatocellular carcinoma(HCC) development and progression and can be a promising molecular target for the development of new diagnostic and therapeutic strategies for HCC.<ref name="ref1" />
 +
 +
===Expression===
 +
The primer designed for HTA is described as the following: HTA of 607 bp, 5�-GGCTTACACATGCTCTTGCT-3�, (sense) and 5�-GCCGAGTTCACTCATCCTTCT-3� (antisense);<ref name="ref1" />
 +
HTA was highly expressed in hepatocellular carcinoma line HepG2, but was not detected in other cell lines.<ref name="ref1" />
 +
 +
===Diseases===
 +
* Hepatocellular carcinoma
 +
 
===Sequence===
 
===Sequence===
 
>gi|238859661|ref|NR_027756.1| Homo sapiens hepatocellular carcinoma associated transcript 5 (non-protein coding) (HCCAT5), long non-coding RNA
 
>gi|238859661|ref|NR_027756.1| Homo sapiens hepatocellular carcinoma associated transcript 5 (non-protein coding) (HCCAT5), long non-coding RNA
 
<dnaseq>AAGTTTAAGACAGCCTGGTGAGGCCCAGAGCCTCACCAGTCCCCCAGAAAACGGAGTATTGTTTCCATCCAAACCTTGCACTGAAAGGAGCCTGTCAGCAGGAAGTGACCTCGTGAGACAACTGTGGGGAGAGCAAAGGGCCGGGGAGAGAAAGGCCTCATTCTCACTGCAAACAGGAAAAGGAAAGAGAAAAAGCAAGCTCTGTCTCCACACAAGGTTTGCTGGGCTGGCTATGAACTGTTCCAGTACGTTCCATCAAATAGACGCCTTCATAGAATCAAGCCGAGCGCGAACGCCGTGTCTGGGGCTCCCACTCCCGGGACACACACGCGGGCTGGCTTACACATGCTCTTGCTCTCTCGCGCTCTGGGAGAGCGCTTATATGGGCTTCATGAGGCTAAGTAATAAACACTTTGTCTTCACCCTGCTATTTATGGGTTGCTTGGGGCATCCTGTGCTCTCCACTGCCCTTACCTGAACAGACGGCTCATGCAGACCCGGAGTTTAATAGGGACAACAGTAAATCTGAGAGGCTGTGTGTGTCCCACGCGCTCCTGTTTTCCCAGCCACCCATGCTAGTTGCAGAGAAAAGCCAACCTGTATCCCTTCGTTTATGCTCTGTGTGCCCTTCCTGGAGAGATCCCTTCATTCTTCAGCAATGGATCAAAGAACTCTGAAAACAAGAACAACCCCGACAGCTGCAAACCACGAGCCCTCACCTCCAGCAGAGGTTTTCGGGAAACTCTGGACGACCACGCGCATGCAGAGGGCTCTCAGAGCTTCCAGGTCCTGTAAGAAGAGATGGAGTCATAGCTGCGCCCTGTCCACTCTCGGGCTGTCACACAAGCCTGGAGCCCAGCCATTTCTCGGCCTTGTCTTCATCTTGGGCTAACCGGTCGTCTCCTGCAAACAGACAGCACGGAGAAGGATGAGTGAACTCGGCCTCTCCCCACAGAATACAGTTCGCCATTACAGCGCTGATTAAATACAGGACATTATCTCACCATAATGCCCTCCTGGCGGCGTTCCCAGGAAAATTCTAACTAATCATAAAAATAGAAAGAAAAACGCAACCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA</dnaseq>
 
<dnaseq>AAGTTTAAGACAGCCTGGTGAGGCCCAGAGCCTCACCAGTCCCCCAGAAAACGGAGTATTGTTTCCATCCAAACCTTGCACTGAAAGGAGCCTGTCAGCAGGAAGTGACCTCGTGAGACAACTGTGGGGAGAGCAAAGGGCCGGGGAGAGAAAGGCCTCATTCTCACTGCAAACAGGAAAAGGAAAGAGAAAAAGCAAGCTCTGTCTCCACACAAGGTTTGCTGGGCTGGCTATGAACTGTTCCAGTACGTTCCATCAAATAGACGCCTTCATAGAATCAAGCCGAGCGCGAACGCCGTGTCTGGGGCTCCCACTCCCGGGACACACACGCGGGCTGGCTTACACATGCTCTTGCTCTCTCGCGCTCTGGGAGAGCGCTTATATGGGCTTCATGAGGCTAAGTAATAAACACTTTGTCTTCACCCTGCTATTTATGGGTTGCTTGGGGCATCCTGTGCTCTCCACTGCCCTTACCTGAACAGACGGCTCATGCAGACCCGGAGTTTAATAGGGACAACAGTAAATCTGAGAGGCTGTGTGTGTCCCACGCGCTCCTGTTTTCCCAGCCACCCATGCTAGTTGCAGAGAAAAGCCAACCTGTATCCCTTCGTTTATGCTCTGTGTGCCCTTCCTGGAGAGATCCCTTCATTCTTCAGCAATGGATCAAAGAACTCTGAAAACAAGAACAACCCCGACAGCTGCAAACCACGAGCCCTCACCTCCAGCAGAGGTTTTCGGGAAACTCTGGACGACCACGCGCATGCAGAGGGCTCTCAGAGCTTCCAGGTCCTGTAAGAAGAGATGGAGTCATAGCTGCGCCCTGTCCACTCTCGGGCTGTCACACAAGCCTGGAGCCCAGCCATTTCTCGGCCTTGTCTTCATCTTGGGCTAACCGGTCGTCTCCTGCAAACAGACAGCACGGAGAAGGATGAGTGAACTCGGCCTCTCCCCACAGAATACAGTTCGCCATTACAGCGCTGATTAAATACAGGACATTATCTCACCATAATGCCCTCCTGGCGGCGTTCCCAGGAAAATTCTAACTAATCATAAAAATAGAAAGAAAAACGCAACCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA</dnaseq>
 +
 +
==Labs working on this lncRNA==
 +
* Tumor Immunobiology Laboratory of Cancer Research Institute,Central South University, 410078 Changsha, Hunan, China <ref name="ref1" />.
 +
 +
==References==
 +
<references>
 +
<ref name="ref1">Yan L,Y. L, Fj.G, Miao Dai, Jj.Wang, Jinyue.Hu and Guancheng Li.(2010) Identification of HTA as a novel-specific marker for human hepatocellular carcinoma.J Cancer Res Clin Oncol,136:1187–1192.</ref>(1)
 +
</references>

Revision as of 02:47, 17 September 2016

Annotated Information

Approved Symbol

HCCAT5

Approved Name

hepatocellular carcinoma associated transcript 5 (non-protein coding)

Synonyms

HTA, FJ222407

Chromosome

16q22.3

RefSeq ID

NR_027756

OMIM ID

615613

Ensembl ID

ENSG00000260880

pubmed IDs

20130911, 23314567

Functions

HTA could play important roles in Hepatocellular carcinoma(HCC) development and progression and can be a promising molecular target for the development of new diagnostic and therapeutic strategies for HCC.[1]

Expression

The primer designed for HTA is described as the following: HTA of 607 bp, 5�-GGCTTACACATGCTCTTGCT-3�, (sense) and 5�-GCCGAGTTCACTCATCCTTCT-3� (antisense);[1] HTA was highly expressed in hepatocellular carcinoma line HepG2, but was not detected in other cell lines.[1]

Diseases

  • Hepatocellular carcinoma

Sequence

>gi|238859661|ref|NR_027756.1| Homo sapiens hepatocellular carcinoma associated transcript 5 (non-protein coding) (HCCAT5), long non-coding RNA

000001 AAGTTTAAGA CAGCCTGGTG AGGCCCAGAG CCTCACCAGT CCCCCAGAAA ACGGAGTATT GTTTCCATCC AAACCTTGCA 000080
000081 CTGAAAGGAG CCTGTCAGCA GGAAGTGACC TCGTGAGACA ACTGTGGGGA GAGCAAAGGG CCGGGGAGAG AAAGGCCTCA 000160
000161 TTCTCACTGC AAACAGGAAA AGGAAAGAGA AAAAGCAAGC TCTGTCTCCA CACAAGGTTT GCTGGGCTGG CTATGAACTG 000240
000241 TTCCAGTACG TTCCATCAAA TAGACGCCTT CATAGAATCA AGCCGAGCGC GAACGCCGTG TCTGGGGCTC CCACTCCCGG 000320
000321 GACACACACG CGGGCTGGCT TACACATGCT CTTGCTCTCT CGCGCTCTGG GAGAGCGCTT ATATGGGCTT CATGAGGCTA 000400
000401 AGTAATAAAC ACTTTGTCTT CACCCTGCTA TTTATGGGTT GCTTGGGGCA TCCTGTGCTC TCCACTGCCC TTACCTGAAC 000480
000481 AGACGGCTCA TGCAGACCCG GAGTTTAATA GGGACAACAG TAAATCTGAG AGGCTGTGTG TGTCCCACGC GCTCCTGTTT 000560
000561 TCCCAGCCAC CCATGCTAGT TGCAGAGAAA AGCCAACCTG TATCCCTTCG TTTATGCTCT GTGTGCCCTT CCTGGAGAGA 000640
000641 TCCCTTCATT CTTCAGCAAT GGATCAAAGA ACTCTGAAAA CAAGAACAAC CCCGACAGCT GCAAACCACG AGCCCTCACC 000720
000721 TCCAGCAGAG GTTTTCGGGA AACTCTGGAC GACCACGCGC ATGCAGAGGG CTCTCAGAGC TTCCAGGTCC TGTAAGAAGA 000800
000801 GATGGAGTCA TAGCTGCGCC CTGTCCACTC TCGGGCTGTC ACACAAGCCT GGAGCCCAGC CATTTCTCGG CCTTGTCTTC 000880
000881 ATCTTGGGCT AACCGGTCGT CTCCTGCAAA CAGACAGCAC GGAGAAGGAT GAGTGAACTC GGCCTCTCCC CACAGAATAC 000960
000961 AGTTCGCCAT TACAGCGCTG ATTAAATACA GGACATTATC TCACCATAAT GCCCTCCTGG CGGCGTTCCC AGGAAAATTC 001040
001041 TAACTAATCA TAAAAATAGA AAGAAAAACG CAACCTAAAA AAAAAAAAAA AAAAAAAAAA AAAAAAAAAA AAAA

Labs working on this lncRNA

  • Tumor Immunobiology Laboratory of Cancer Research Institute,Central South University, 410078 Changsha, Hunan, China [1].

References

  1. 1.0 1.1 1.2 1.3 Yan L,Y. L, Fj.G, Miao Dai, Jj.Wang, Jinyue.Hu and Guancheng Li.(2010) Identification of HTA as a novel-specific marker for human hepatocellular carcinoma.J Cancer Res Clin Oncol,136:1187–1192.