ITGA6-AS1

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ITGA6-AS1, a set of biomarkers for the prognosis of patients with GBM,enabling a moreaccurate prediction of survival and revealingmorebiological functions.

Annotated Information

Approved Symbol

ITGA6-AS1

Approved Name

ITGA6-AS1: ITGA6 antisense RNA 1, AC078883.3

Characteristics

ITGA6-AS1 is a long noncoding RNA with esemble id ENSG00000232788, and is located on chromosome 2q31.1 [1].

Function

ITGA6-AS1 is enriched with ion binding, transport, cell-cell signaling, plasmamembrane parts, and more, and they were mainly related to neuroactive ligand-receptor interaction pathway, calcium signaling pathway, and the mitogen-activated protein kinase signaling pathway [1].

Regulation

NA

Diseases

  • Glioblastoma [1].

Expression

ITGA6-AS1 is expressed in brain tissues [1].

Labs working on this lncRNA

  • Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
  • Department of Neurosurgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, People's Republic of China.

References

  1. ↑ 1.0 1.1 1.2 1.3 Lei BX, Yu L, Jung TA, Deng YF, Xiang W, Liu YW et al. Prospective Series of Nine Long Noncoding RNAs Associated with Survival of Patients with Glioblastoma[J]. J Neurol Surg Part A. 2018, 79(6):471-478.

Sequence

>gi|101929947|ref|NR_157573.1|Homo sapiens ITGA6 antisense RNA 1 (ITGA6-AS1), long non-coding RNA

000001 GCATGTGAGA ACTTTTGGCT GATGAATACA AGATACGCTC ATTCATTCTC TTCATTGCTA TGAAATGAGT TTTTCCACAA 000080
000081 CCTCCTGCAG AACCTCAACA CATCACTAGG TGGCAACATC CCTACACCAT ATCGGTTTAG AAACCACGGT TAGGAGGAGC 000160
000161 AGCAAAACAC GCGGCATCCC AGTATGATTC AGAAGTAAAG TTTACAATCT TTGAGGCCTG GCTGACTCAT GGAACAACTA 000240
000241 GGACAAGAAA CAAAGACAAA GAACACACAC CTGACTGGAC AGAGATAAAC CAAGAGCTGA GAGTTTTGGA AACAAGGCTG 000320
000321 GAGCTGAGGA AAAGGACTGG GAACACGAAC CTGTACAAAC AACAAATTCT TACAACAGAA AACAAGCCAC TCCTGGCCAT 000400
000401 CAAGAAACCC ACAAATCTCA GAAGCAAAAG CAAAACAAAT GAAAATACAA ACCAAATAGT CTCTATTACC TTCATGCCTG 000480
000481 TTGGGTCCCA ATAAAGGAAT CATTCCAATA AA
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