Difference between revisions of "MT-LIPCAR"

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(Created page with "==Annotated Information== ===Approved Symbol=== MT-LIPCAR ===Approved Name=== mitochondrially encoded long non-coding cardiac associated RNA ===Previous Symbols=== ===Synonym...")
 
 
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===Chromosome===
 
===Chromosome===
 
mitochondria
 
mitochondria
===OMIM ID===
+
===Disease===
_
+
heart failure
===Ensembl ID===
 
_
 
 
===pubmed IDs===
 
===pubmed IDs===
 
24663402
 
24663402
 +
 +
===Characteristics===
 +
LIPCAR, a long intergenic noncoding RNA predicting cardiac remodeling and survival of patients with HF.<ref name="ref1" />.
 +
 +
===Cellular Localization===
 +
A mitochondrial long noncoding RNA.<ref name="ref1" />.
 +
 +
===Function===
 +
LIPCAR is a novel biomarker of cardiac remodeling and predicts future death in patients with heart failure.<ref name="ref1" />
 +
 +
===Regulation===
 +
The mitochondrial long noncoding RNA uc022bqs.1 (LIPCAR) was downregulated early after myocardial infarction but upregulated during later stages.<ref name="ref1" />.
 +
 +
===Diseases===
 +
* heart failure
 +
 +
===Expression===
 +
LIPCAR are downregulated at baseline, but significantly upregulated later on during the development of HF.<ref name="ref1" />
 +
 +
==Labs working on this lncRNA==
 +
* From the Institute of Molecular and Translational Therapeutic Strategies (IMTTS), IFB-Tx (R.K., I.V., J.F., A.H., T.T.) and REBIRTH Excellence Cluster (T.T.), Hannover Medical School, Hannover, Germany; Inserm, U744, University Lille Nord de France, Lille, France (C.B., F.M., G.L., P.d.G., F.P.); Institut Pasteur de Lille, Lille, France (C.B., F.M., G.L., P.d.G., F.P.); Centre Hospitalier Régional et Universitaire de Lille, Lille, France (C.B., G.L., P.d.G., F.P.); Faculté de Médecine de Lille, Lille, France (C.B., G.L.); and National Heart and Lung Institute, Imperial College London, London, United Kingdom (T.T.). <ref name="ref1" />.
 +
 +
==References==
 +
<references>
 +
<ref name="ref1"> Kumarswamy R, Bauters C, Volkmann I, Maury F, Fetisch J, Holzmann A, Lemesle G, de Groote P, Pinet F, Thum T.(2014) Circulating Long Noncoding RNA, LIPCAR, Predicts Survival in Patients With Heart Failure.</ref>(1)
 +
</references>

Latest revision as of 12:30, 1 July 2016

Annotated Information

Approved Symbol

MT-LIPCAR

Approved Name

mitochondrially encoded long non-coding cardiac associated RNA

Previous Symbols

Synonyms

uc022bqs.1, LIPCAR

Chromosome

mitochondria

Disease

heart failure

pubmed IDs

24663402

Characteristics

LIPCAR, a long intergenic noncoding RNA predicting cardiac remodeling and survival of patients with HF.[1].

Cellular Localization

A mitochondrial long noncoding RNA.[1].

Function

LIPCAR is a novel biomarker of cardiac remodeling and predicts future death in patients with heart failure.[1]

Regulation

The mitochondrial long noncoding RNA uc022bqs.1 (LIPCAR) was downregulated early after myocardial infarction but upregulated during later stages.[1].

Diseases

  • heart failure

Expression

LIPCAR are downregulated at baseline, but significantly upregulated later on during the development of HF.[1]

Labs working on this lncRNA

  • From the Institute of Molecular and Translational Therapeutic Strategies (IMTTS), IFB-Tx (R.K., I.V., J.F., A.H., T.T.) and REBIRTH Excellence Cluster (T.T.), Hannover Medical School, Hannover, Germany; Inserm, U744, University Lille Nord de France, Lille, France (C.B., F.M., G.L., P.d.G., F.P.); Institut Pasteur de Lille, Lille, France (C.B., F.M., G.L., P.d.G., F.P.); Centre Hospitalier Régional et Universitaire de Lille, Lille, France (C.B., G.L., P.d.G., F.P.); Faculté de Médecine de Lille, Lille, France (C.B., G.L.); and National Heart and Lung Institute, Imperial College London, London, United Kingdom (T.T.). [1].

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Kumarswamy R, Bauters C, Volkmann I, Maury F, Fetisch J, Holzmann A, Lemesle G, de Groote P, Pinet F, Thum T.(2014) Circulating Long Noncoding RNA, LIPCAR, Predicts Survival in Patients With Heart Failure.