Difference between revisions of "Main Page"

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*[[File:New5.png]][[LncRNAWiki:Featured|Featured LncRNAs]]
 
*[[File:New5.png]][[LncRNAWiki:Featured|Featured LncRNAs]]
 
*[[File:New5.png]][[LncRNAWiki:Small_proteins|Small Proteins]]
 
*[[File:New5.png]][[LncRNAWiki:Small_proteins|Small Proteins]]
*[[File:New5.png]][[LncRNAWiki:Disease|Disease]]
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*[[File:New5.png]][[LncRNAWiki:Disease|Diseases]]
 
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<div style="padding:0.5em 0.5em;">[[File:Featured2.png|left|410px|caption]]  
 
<div style="padding:0.5em 0.5em;">[[File:Featured2.png|left|410px|caption]]  
  
LncRNAWiki keeps frequent updates by community annotation of human lncRNAs and integration of newly identified lncRNAs with experimental evidence. In contrast to the previous version that had 86 curated lncRNAs, the updated version has a total of 948 lncRNAs that are community-curated ([[LncRNAWiki:Featured|Featured lncRNAs]]).
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In contrast to the previous version that had 86 curated lncRNAs, the updated version has a total of 948 lncRNAs that are community-curated ([[LncRNAWiki:Featured|Featured lncRNAs]]).
  
  
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===<u>Top 10 Diseases</u>===
 
===<u>Top 10 Diseases</u>===
  
* 213 Cancer  
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* 212 [[LncRNAWiki:Cancer|Cancer]]
  
* 39 Nervous System Diseases
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* 37 [[LncRNAWiki:Nervous System Diseases|Nervous System Diseases]]
  
* 33 Congenital, Hereditary, and Neonatal Diseases  
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* 22 [[LncRNAWiki:Cardiovascular Diseases|Cardiovascular Diseases]]
  
* 21 Musculoskeletal Diseases
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* 21 [[LncRNAWiki:Congenital, Hereditary, and Neonatal Diseases and Abnormalities|Congenital, Hereditary, and Neonatal Diseases and Abnormalities]]
  
* 21 Hemic and Lymphatic Diseases 21 Mental Disorders
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* 20 [[LncRNAWiki:Musculoskeletal Diseases|Musculoskeletal Diseases]]
  
* 19 Cardiovascular Diseases 15 Nutritional and Metabolic Diseases
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* 19 [[LncRNAWiki:Hemic and Lymphatic Diseases|Hemic and Lymphatic Diseases]]
  
* 15 Endocrine System Diseases 10 Skin and Connective Tissue Diseases
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* 18 [[LncRNAWiki:Endocrine System Diseases|Endocrine System Diseases]]
  
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* 14 [[LncRNAWiki:Mental Disorders|Mental Disorders]]
  
Among these 948 featured lncRNAs, 404 have been experimentally proved to be associated with cancer and other diseases  ([[LncRNAWiki:Disease|Disease]]).
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* 9 [[LncRNAWiki:Skin and Connective Tissue Diseases|Skin and Connective Tissue Diseases]]
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* 9 [[LncRNAWiki:Nutritional and Metabolic Diseases|Nutritional and Metabolic Diseases]]
  
 
''Top diseases and the lncRNA numbers are listed.''
 
''Top diseases and the lncRNA numbers are listed.''
 
 
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Classification</div>
 
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Classification</div>
 
<div style="padding:0.5em 0.5em;">[[File:web2a.png|left|410px]]  
 
<div style="padding:0.5em 0.5em;">[[File:web2a.png|left|410px]]  
The majority of the lncRNA information was initially seeded with a subset of information from [http://www.gencodegenes.org/ GENCODE], [http://www.bioinfo.org/noncode/ NONCODE], [http://www.lncipedia.org/ LNCipedia], and [http://www.lncrnadb.org/ lncRNAdb], and we classified these lncRNAs into seven groups based on their genomic location in respect to protein-coding genes (Ma etal. 2013, RNA Biology). [[Help:Contents#Database content|''Help'']]
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We classified these lncRNAs into seven groups based on their genomic location in respect to protein-coding genes (Ma etal. 2013, RNA Biology). [[Help:Contents#Database content|''Help'']]
 
<br /></div>
 
<br /></div>
  
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<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Small proteins</div>
 
<div style="background:#ACD6FF; border-bottom:1px solid #66B3FF; padding:0.2em 0.5em; font-size:125%; font-weight:bold;">Small proteins</div>
 
<div style="padding:0.5em 0.5em;">[[File:SmallPRO-1.png|left|330px]]  
 
<div style="padding:0.5em 0.5em;">[[File:SmallPRO-1.png|left|330px]]  
We developed computational approaches for identification of small proteins in all the human lncRNAs in LncRNAWiki.
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We identified '''9,387''' lncRNAs potentially encoding small proteins and '''2,246''' among them are with high confidence ([[LncRNAWiki:small proteins|lncRNAs and small proteins]], [[Help:Contents#Database content|Help]]).  
 
 
As a result, we identified '''9,387''' lncRNAs potentially encoding small proteins and '''2,246''' among them are with high confidence ([[LncRNAWiki:small proteins|lncRNAs and small proteins]], [[Help:Contents#Database content|Help]]).  
 
 
<br /></div>
 
<br /></div>
  

Revision as of 03:56, 29 June 2017


Welcome to LncRNAWiki
106,053 human long non-coding RNAs inside
Introduction

LncRNAWiki is a wiki-based, publicly editable and open-content platform for community curation of human long non-coding RNAs (lncRNAs), viz., a community-curated lncRNA knowledgebase. Unlike conventional biological databases based on expert curation, lncRNAWiki harnesses collective intelligence to collect, edit and annotate information about lncRNAs, quantifies users' contributions in each annotated lncRNA and provides explicit authorship to encourage more participation from the whole scientific community.

Imagine a world in which every single person on the planet has free access to the sum of all human knowledge. — Jimmy Wales, Founder of Wikipedia

Featured lncRNAs
caption

In contrast to the previous version that had 86 curated lncRNAs, the updated version has a total of 948 lncRNAs that are community-curated (Featured lncRNAs).



Diseases

Top 10 Diseases

Top diseases and the lncRNA numbers are listed.

Classification
Web2a.png

We classified these lncRNAs into seven groups based on their genomic location in respect to protein-coding genes (Ma etal. 2013, RNA Biology). Help



Small proteins
SmallPRO-1.png

We identified 9,387 lncRNAs potentially encoding small proteins and 2,246 among them are with high confidence (lncRNAs and small proteins, Help).


How to Cite

If you use any data or information in your work, please cite the following primary publication:

Related publication:

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