Difference between revisions of "NONHSAT112472"

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Please input one-sentence summary here.
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TDRG1, a developmentaly related testicular-specific gene, which was located in chromosome 6p21.1-p21.2 with 1197 bp in length, may involve in normal human spermatogenesis and fertilization.
  
 
==Annotated Information==
 
==Annotated Information==
 
===Transcriptomic Nomeclature===
 
===Transcriptomic Nomeclature===
Please input transcriptomic nomeclature information here.
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TDRG1:testis development related 1 (non-protein coding)(HGNC nomenclature)
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===characteristics===
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TDRG1 was 1197 bp in length, located in chromosome 6p21.1-p21.2. The sequence of the open reading frame was 504-806bp. The cDNA encodes a novel protein of 100 amino acids.  TDRG1 is exclusively expressed in the testis but not in any other non-reproductive tissues. TDRG1 is mainly located in spermatogenic cells in seminiferous tubules of adult testis<ref name="ref1" />.
  
 
===Function===
 
===Function===
Please input function information here.
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G1 is a human testis-specific gene and may  play important roles in normal human spermatogenesis<ref name="ref1" />.
  
===Regulation===
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===Disease===
Please input regulation information here.
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testicular cancer
  
 
===Expression===
 
===Expression===
Please input expression information here.
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TDRG1 is specially expressed in spermatogenic cells, with highest expression level during human puberty stage, and decresing levels of expression with aging<ref name="ref1" />.  
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Primers for regular RT-PCR and real time RT-PCR were as follows,
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{|class='wikitalbe' style="text-align:center"
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|-
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! | Primers
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! | RT-PCR
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! | real time RT-PCR
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|-
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| | TDRG1
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| | 5'-AAGAGGAGGGAGGCAGTCT-3'
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| | 5'-GCCCAATTCCTCTTGACTGA-3'<ref name="ref1" />
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|-
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| | GAPDH
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| | 5'-CCACCCATGGCAAATTCCATGGCA-3'
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| | 5'-TCTAGACGGCAGGTCAGGTCACC-3'<ref name="ref1" />
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|}
  
 
===Allelic Information and Variation===
 
===Allelic Information and Variation===
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==Labs working on this lncRNA==
 
==Labs working on this lncRNA==
Please input related labs here.
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* Department of Urology, the Third Xiangya Hospital of Central South University, Changsha, Hunan, PR China.<ref name="ref1" />
  
 
==References==
 
==References==
Please input cited references here.
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<references>
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<ref name="ref1">Jiang X, Li D, Yang J, Wen J, Chen H, Xiao X, et al. Characterization of a novel human testis-specific gene: testis developmental related gene 1 (TDRG1)[J]. The Tohoku journal of experimental medicine. 2011,225(4):311-8.</ref>(1)
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</references>
  
 
{{basic|
 
{{basic|
 
tID = NONHSAT112472|
 
tID = NONHSAT112472|
 
source = NONCODE4.0|
 
source = NONCODE4.0|
same = ,|
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same =TDRG1 ,|
 
classification = intergenic|
 
classification = intergenic|
 
length = 1085 nt|
 
length = 1085 nt|

Latest revision as of 14:33, 1 July 2016

TDRG1, a developmentaly related testicular-specific gene, which was located in chromosome 6p21.1-p21.2 with 1197 bp in length, may involve in normal human spermatogenesis and fertilization.

Annotated Information

Transcriptomic Nomeclature

TDRG1:testis development related 1 (non-protein coding)(HGNC nomenclature)

characteristics

TDRG1 was 1197 bp in length, located in chromosome 6p21.1-p21.2. The sequence of the open reading frame was 504-806bp. The cDNA encodes a novel protein of 100 amino acids. TDRG1 is exclusively expressed in the testis but not in any other non-reproductive tissues. TDRG1 is mainly located in spermatogenic cells in seminiferous tubules of adult testis[1].

Function

G1 is a human testis-specific gene and may play important roles in normal human spermatogenesis[1].

Disease

testicular cancer

Expression

TDRG1 is specially expressed in spermatogenic cells, with highest expression level during human puberty stage, and decresing levels of expression with aging[1]. Primers for regular RT-PCR and real time RT-PCR were as follows,

Primers RT-PCR real time RT-PCR
TDRG1 5'-AAGAGGAGGGAGGCAGTCT-3' 5'-GCCCAATTCCTCTTGACTGA-3'[1]
GAPDH 5'-CCACCCATGGCAAATTCCATGGCA-3' 5'-TCTAGACGGCAGGTCAGGTCACC-3'[1]

Allelic Information and Variation

Please input allelic information and variation information here.

Evolution

Please input evolution information here.

You can also add sub-section(s) at will.

Labs working on this lncRNA

  • Department of Urology, the Third Xiangya Hospital of Central South University, Changsha, Hunan, PR China.[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Jiang X, Li D, Yang J, Wen J, Chen H, Xiao X, et al. Characterization of a novel human testis-specific gene: testis developmental related gene 1 (TDRG1)[J]. The Tohoku journal of experimental medicine. 2011,225(4):311-8.

Basic Information

Transcript ID

NONHSAT112472

Source

NONCODE4.0

Same with

TDRG1 ,

Classification

intergenic

Length

1085 nt

Genomic location

chr6+:40345782..40347638

Exon number

2

Exons

40345782..40346636,40347021..40347638

Genome context

Sequence
000001 AAGATCAGGA CTGCTGAAAG AATGAAGAAG AACTTACTTG GCCTAGGATG TGGCTAGAGA ACGGAGCGCA CTTTCACTTA 000080
000081 CCTGGCAAGG TGGTTTTGGA AGTTTCCACG GAAGCCTTCC CAGGGCCGCT GCTGCCCGTC CTCGCCTAGG TGTGGAGCTT 000160
000161 CCCGACCGGC TGGGGAGGGA ATGTCCTGCG GGAGCCGCCG AGGACCCTCT TTAGCCTCTT CCCTGGCTTG GCTGCAGCTG 000240
000241 CAGTCTGGTA CTCGCCCATT CTGCTCTTCT TCACCTCCGT ATTTTCTCTC TCACGGAAGA AGAATTCCAT TCTCCCATCC 000320
000321 CAGGAAGGAG AGTGCCCTGC GTGCCACGAA AGAGCCCAGG ACCCACAGGA CAAATACGTC ACTGGCAGAC CTGCCTTCGC 000400
000401 CAGCGCCAGC CCATCTCTGA AACCTCCAGC ATTTGTGCCC CGGTCCGGCC CCTCCCAGGC CTGACTCTTT CCGTGAACGG 000480
000481 TCACTGCGCA GGATCAAGCT ACAATGAAGA GGAGGGAGGC AGTCTGCGCG CACCGCCATT TTCTAGGAAC TGGGAAGCCC 000560
000561 CCCCACCCCT TAGGAAGATC CATCCCTGTG GAACCTTGCC CAGGCTTACC AGCCTTTGCT GAGGTTGATC TATTGTCCCT 000640
000641 CCTTGTCCCC ATCAAAATAT CCAGCACTCC ACCTTCAGGG AGTAGACTTG ACCCTCAAAT AGCAAGTTCA GCCTTCCCAG 000720
000721 GTCTAGGTTC CCTGGGAGGT CAAGATTCGT CTGGTTCCTT AGTACAGAGG GCTAGCTGTG AGTTGGAATC CCCCTATGAG 000800
000801 CTTTAGAATC AGTCAAGAGG AATTGGGCCC CTTCCCTTCA TCCCTCTTCT TTTCCCTTTT TGTCCCAGAG CTCAGCTCTG 000880
000881 ACTCAAAAGT TTTTCCATTT ACCATCAACA TGGAAACTTG GCTCCTCACG TAGGTATATT ATCCCCCTTT TGTACATGGT 000960
000961 CTTGTTGATC CAAACTCCCT TTCTGTGAAA GAGGCCTGTG GGGCTCAAGA AGCCTGGTCA GCCAGCCAGG CTAGTCCCAC 001040
001041 ATACCTCAGA ACCAGTTTAA TAAAGGCTCT ATGTCATTCT TTTTT
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