NONHSAT122932

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Annotated Information

Name

ST7OT Characteristics

Characteristics

Four noncoding RNAs from the RAY1/ST7 gene locus. Complex gene locus with a large number of coding and noncoding isoforms. ST7OT1 & 2 are antisense to ST7. ST7OT3 & 4 are on the sense strand. ST7OT1 - ~2kb unspliced antisense transcript that initiates in intron 1 of ST7, covers the first exon and terminates in the ST7 promoter region. Polyadenylated. Nb: it also overlaps exon 1 of ST7OT4. ST7OT2 - Spliced antisense transcripts. Multiple isoforms that share either some 5' or some 3' exons. Isoforms are between 900-1300 bp, with 4-6 exons and polyadenlyated. ST7OT3 - Spliced ~1kb transcript. Begins in intron 10 of ST7, shares exons 11-13 and sometimes 14 & 15 with ST7 plus has a number of unique exons. Some exons may also act as a alternative 3' end for ST7. ST7OT4 - Multiple spliced transcripts within the long first intron of ST7. However, Refseq ST7OT4 transcript may be protein coding. Transcription begins just ~200bp downstream from the end of first ST7 exon.

Function

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Expression

ST7OT1 - abundantly expressed in testis, also expressed in cerebellum, skeletal muscle, uterus, cerebellum, spinal cord, fetal brain, and prostate. ST7OT2 - testis, fetal brain, cerebellum, mammary gland, fibroblasts. ST7OT3 - expression only detected in cerebellum. ST7OT4 - no expression detected.

Conservation

ST7OT1 - some conserved sequence with mouse, most of this is where ST7OT1 overlaps the first exon of ST7 however. ST7OT2 - 3' end of some isoforms shows some conservation with mouse. ST7OT3 - some conserved sequence, most of this is shared exons with ST7 though. ST7OT4 - sequence not conserved with mouse.

Misc

ST7OT1 - NCBI Gene ID: 93653. ST7OT2 - NCBI Gene ID: 93654. ST7OT3 - NCBI Gene ID: 93655. ST7OT4 - NCBI Gene ID: 338069

Transcriptomic Nomeclature

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Regulation

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Allelic Information and Variation

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Evolution

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Labs working on this lncRNA

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References

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Basic Information

Transcript ID	NONHSAT122932
Source	NONCODE4.0
Same with	,
Classification	sense
Length	1052 nt
Genomic location	chr7+:116822735..116849991
Exon number	9
Exons	116822735..116822799,116824179..116824253,116829375..116829447,116830187..116830322,116830888..116830990,116831689..116831815,116838374..116838589,116839125..116839198,116849841..116849991
Genome context
Sequence	000001 TGGTATTCAG AGACGTAGAG TGGCACAGCT CCTCAGACTG CACGTTTTCC CTGAGCTCTC TACTGGAAAA CATTTCTATA 000080 000081 AAACATAAGA TGGCAAAGAG GTGGAAGAAA AATTAATGCC AGCAGTTCAG CTTTGACTAA ATATAAGCTT ACCAAAGTCA 000160 000161 GCAACAATAT GCTACACAGC TGCTTTGCTC AAAGCAAGAG CTGTCTCTGA CAAATCGCCA GTACCTACTG CAACATCTTT 000240 000241 TCTCCCTACA CAGCGACTCC AGCTTGGGAG GGCAGGGCCA GGGTTGTCAC AGCTTCCCCT GTGGTGTCTG CCTGCCAAGC 000320 000321 ACAGCTCTGG AGTTAGCCCT GGGTGTGAGA TTCTCTCCTG AGGCTGCATC TCGGCGGGGG CTGAGCACAG CAGAGATGAA 000400 000401 TGCAGTAGAG GCCATTCATA GAGCTGTGGA ATTCAATCCT CATGTGCCAA AATATCTACA TGCTGTATTA CGTAATTATC 000480 000481 ATCTTCTCTG AGGGAGGAAA AAAAGTAGCT GAGAGCCACT TTCAGTCCCG CTATTAAGTA CATTTTGGCC TCTAAGAAAC 000560 000561 TTCGTGTGGT TCACCTCAGG CTAGGTGGAA ATAGAGGCTG CCTAGAAACA TGCATTAACA GGTGCTTCTT GGGCCACCCT 000640 000641 AGCCTGAAGA AGGACAACCA GAGAGTATAA CAGTGGCACC TCAATGCCTT GGCCTTGAGG ACCCTCAGTG TCCCTTCAGG 000720 000721 CCTCCAGATT TGAGGGGAGG CTCTAGCATG TTCTGGCTGC AGCTATTGTC TTCAGGGATT CTGCAGCTTG TAGCTCGTTG 000800 000801 GGGTACTTCT ACCAATTGGA GCTGGGCTGT TGGAGTCATC TCCACTGCCT ACCACCAGGA CAAGCAGAGA AGTTACCTAC 000880 000881 TAGAAATGAA AAGCTTAATC CTACCCCCAG AACATATCCT GAAGAGAGGA GACAGTGAAG CAATAGCATA TGCATTCTTT 000960 000961 CATCTTGCAC ACTGGAAGAG AGTGGAAGGG GCTTTGAATC TTTTGCATTG TACGTGGGAA GGCACTTTTC GAAAAAAAAA 001040 001041 AAAAAAAAAA AA

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