PRDM16-DT

From LncRNAWiki
Revision as of 05:34, 10 August 2019 by Lin Liu (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search

Annotated Information

Name

PRDM16-DT

The expression of PRDM16-DT is needed for brown adipogenesis.[1].

Alias

lnc-dPrdm16

ID

ENSG00000177133

Function

Knockdown PRDM16-DT could impair brown adipocyte differentiation in vitro.[1] The expression of PRDM16-DT is required for iWAT browning.[1] lnc-dPrdm16 is a regulator in BAT and during inguinal WAT browning in vivo.[1]

Labs working on this lncRNA

  • Key Laboratory of Laboratory Medicine, School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, Zhejiang, 325035, China. cmding@gmail.com.

References

  1. 1.0 1.1 1.2 1.3 Ding C, Lim YC, Chia SY, Walet ACE, Xu S, Lo KA, Zhao Y, Zhu D, Shan Z, Chen Q, Leow MK, Xu D, Sun L. De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis. Nat Commun. 2018 Apr 6;9(1):1329. doi: 10.1038/s41467-018-03754-3. PubMed PMID: 29626186; PubMed Central PMCID: PMC5889397.