Difference between revisions of "PSMD6-AS1"
Guangyu Wang (talk | contribs) (Created page with "==Annotated Information== ===Approved Symbol=== PSMD6-AS1 ===Approved Name=== PSMD6 antisense RNA 1 ===Previous Symbols=== _ ===Synonyms=== "ENST00000462717, lnc00462717" ===C...") |
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==Annotated Information== | ==Annotated Information== | ||
| − | === | + | ===Name=== |
| − | PSMD6-AS1 | + | PSMD6-AS1:PSMD6 antisense RNA 1 |
| − | + | ||
| − | PSMD6 antisense RNA 1 | + | Lnc00462717<ref name="ref1" /> |
| − | === | + | ===Cellular Localization=== |
| − | + | ENST00462717 is located on chromosome 12 upstream of the MDM2 promoter region<ref name="ref1" />. | |
| − | === | + | |
| − | + | ===Function=== | |
| − | === | + | Lnc00462717 overexpression suppresses glioma cell proliferation, survival and migration while knockdown of lnc00462717 has an opposite result.<ref name="ref1" />. |
| − | + | ||
| − | === | + | ===Regulation=== |
| − | + | MDM2 expression is inversely regulated by lnc00462717 in glioma<ref name="ref1" />. | |
| − | === | + | |
| − | + | ===Diseases=== | |
| − | === | + | Gliomas<ref name="ref1" />. |
| − | + | Papillary Thyroid Cancer<ref name="ref2" />. | |
| − | == | + | |
| − | + | ==Labs working on this lncRNA== | |
| + | * EEG Room, Department of Neurology, Qilu Hospital of Shandong University, Shandong 250012, China | ||
| + | *Department of Neurology, Qilu Hospital of Shandong University, Shandong 250012, China | ||
| + | *Department of Medical Insurance Office, Qilu Hospital of Shandong University, Shandong 250012, China<ref name="ref1" />. | ||
| + | *Department of Nuclear Medicine, Shanghai Jiao Tong University Affliated Sixth People’s Hospital, Shanghai, China<ref name="ref2" />. | ||
| + | |||
| + | ==References== | ||
| + | <references> | ||
| + | <ref name="ref1" > | ||
| + | Wang A, Meng M, Zhao X, Kong L. Long non-coding RNA ENST00462717 suppresses | ||
| + | the proliferation, survival, and migration by inhibiting MDM2/MAPK pathway in | ||
| + | glioma. Biochem Biophys Res Commun. 2017 Apr 1;485(2):513-521. | ||
| + | </ref> | ||
| + | |||
| + | <ref name="ref2"> | ||
| + | Qiu ZL, Shen CT, Sun ZK, Wei WJ, Zhang XY, Song HJ, Luo QY. Circulating Long | ||
| + | Non-Coding RNAs Act as Biomarkers for Predicting 131I Uptake and Mortality in | ||
| + | Papillary Thyroid Cancer Patients with Lung Metastases. Cell Physiol Biochem. | ||
| + | 2016;40(6):1377-1390. | ||
| + | </ref> | ||
| + | </references> | ||
Revision as of 08:05, 18 July 2017
Contents
Annotated Information
Name
PSMD6-AS1:PSMD6 antisense RNA 1
Lnc00462717[1]
Cellular Localization
ENST00462717 is located on chromosome 12 upstream of the MDM2 promoter region[1].
Function
Lnc00462717 overexpression suppresses glioma cell proliferation, survival and migration while knockdown of lnc00462717 has an opposite result.[1].
Regulation
MDM2 expression is inversely regulated by lnc00462717 in glioma[1].
Diseases
Gliomas[1]. Papillary Thyroid Cancer[2].
Labs working on this lncRNA
- EEG Room, Department of Neurology, Qilu Hospital of Shandong University, Shandong 250012, China
- Department of Neurology, Qilu Hospital of Shandong University, Shandong 250012, China
- Department of Medical Insurance Office, Qilu Hospital of Shandong University, Shandong 250012, China[1].
- Department of Nuclear Medicine, Shanghai Jiao Tong University Affliated Sixth People’s Hospital, Shanghai, China[2].
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Wang A, Meng M, Zhao X, Kong L. Long non-coding RNA ENST00462717 suppresses the proliferation, survival, and migration by inhibiting MDM2/MAPK pathway in glioma. Biochem Biophys Res Commun. 2017 Apr 1;485(2):513-521.
- ↑ 2.0 2.1 Qiu ZL, Shen CT, Sun ZK, Wei WJ, Zhang XY, Song HJ, Luo QY. Circulating Long Non-Coding RNAs Act as Biomarkers for Predicting 131I Uptake and Mortality in Papillary Thyroid Cancer Patients with Lung Metastases. Cell Physiol Biochem. 2016;40(6):1377-1390.
