Difference between revisions of "PSMD6-AS1"
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===Diseases=== | ===Diseases=== | ||
Gliomas<ref name="ref1" />. | Gliomas<ref name="ref1" />. | ||
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Papillary Thyroid Cancer<ref name="ref2" />. | Papillary Thyroid Cancer<ref name="ref2" />. | ||
Revision as of 08:05, 18 July 2017
Contents
Annotated Information
Name
PSMD6-AS1:PSMD6 antisense RNA 1
Lnc00462717[1]
Cellular Localization
ENST00462717 is located on chromosome 12 upstream of the MDM2 promoter region[1].
Function
Lnc00462717 overexpression suppresses glioma cell proliferation, survival and migration while knockdown of lnc00462717 has an opposite result.[1].
Regulation
MDM2 expression is inversely regulated by lnc00462717 in glioma[1].
Diseases
Gliomas[1].
Papillary Thyroid Cancer[2].
Labs working on this lncRNA
- EEG Room, Department of Neurology, Qilu Hospital of Shandong University, Shandong 250012, China
- Department of Neurology, Qilu Hospital of Shandong University, Shandong 250012, China
- Department of Medical Insurance Office, Qilu Hospital of Shandong University, Shandong 250012, China[1].
- Department of Nuclear Medicine, Shanghai Jiao Tong University Affliated Sixth People’s Hospital, Shanghai, China[2].
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Wang A, Meng M, Zhao X, Kong L. Long non-coding RNA ENST00462717 suppresses the proliferation, survival, and migration by inhibiting MDM2/MAPK pathway in glioma. Biochem Biophys Res Commun. 2017 Apr 1;485(2):513-521.
- ↑ 2.0 2.1 Qiu ZL, Shen CT, Sun ZK, Wei WJ, Zhang XY, Song HJ, Luo QY. Circulating Long Non-Coding RNAs Act as Biomarkers for Predicting 131I Uptake and Mortality in Papillary Thyroid Cancer Patients with Lung Metastases. Cell Physiol Biochem. 2016;40(6):1377-1390.
