As in other organisms, plants undergo age-dependent developmental changes during their lifespans. Leaves, the major photosynthetic organs, undergo growth, maturation, and senescence, and ultimately progress to death along age. As the final stage of leaf development, leaf senescence is a highly ordered process regulated by senescence associated genes (SAGs) and is tightly controlled by multiple layers of regulation, including chromatin, transcriptional and post-transcriptional, as well as translational and post-translational levels.

To facilitate the systematical research and comparative study of leaf senescence, we constructed a database of leaf senescence (LSD 1.0, August 2011; LSD 2.0, June 2013; LSD 3.0, June 2019; LSD 4.0, May 2022) to collect SAGs, mutants, phenotypes and literature references. To cover the significant advances in the field of leaf senescence research and extending the functionality of the database, we update LSD to a new version LSD 5.0 (November 2023).

LSD 5.0 contains 31,740 genes and 1,209 mutants from 148 Species. Resources deposited in LSD are as follows:

. 2850 T-DNA insertion mutants in Arabidopsis
. 29 Leaf senescence-associated transcriptomics
. 1588 Senescence-associated genes (SAGs) in Poplar
. 1935 Senescence-differentially expressed small RNAs
. 78 Proteome data associated with leaf senescence in soybean
. 90 Senescence phenotypes of natural accessions in Arabidopsis
. 1862 Senescence-associated genes(SAGs) in Kalanchoe serrata
. 6076 Proteome data associated with Arabidopsis leaf senescence
. 5234 Senescence-associated alternative splicing variants (Sen-ASVs)
. 37 Senescence-associated transcription factors (Sen-TFs) ChIP- or DAP-seq data
. 2044 Arabidopsis senescence-associated long noncoding RNA in (Sen-AtlncRNA)

Please Cite:

  Leaf Senescence Database v5.0: A Comprehensive Repository for Facilitating Plant Senescence Research. Journal of Molecular Biology 2024.

last update: 1 January 2024