Welcome to LSD 4.0: Leaf Senescence Database Update 2022

As in other organisms, plants undergo age-dependent developmental changes during their lifespans. Leaves, the major photosynthetic organs, undergo growth, maturation, and senescence, and ultimately progress to death along age. As the final stage of leaf development, leaf senescence is a highly ordered process regulated by senescence associated genes (SAGs) and is tightly controlled by multiple layers of regulation, including chromatin, transcriptional and post-transcriptional, as well as translational and post-translational levels.

To facilitate the systematical research and comparative study of leaf senescence, we constructed a database of leaf senescence (LSD 1.0, August 2011; LSD 2.0, June 2013; LSD 3.0, June 2019) to collect SAGs, mutants, phenotypes and literature references. To cover the significant advances in the field of leaf senescence research and extending the functionality of the database, we update LSD to a new version LSD 4.0 (May 2022).

LSD 4.0 contains 31,214 genes and 1,037 mutants from 86 Species. New features of LSD 4.0 are as follows:

. 25,356 genes and 420 mutants from 18 Species were added in LSD 4.0.
. Temporal transcriptome data of leaf senescence in Kalanchoe serrata were integrated.
. Leaf senescence-associated alternative splicing variants (Sen-ASVs) in Poplar and Arabidopsis were included.
. Proteome data associated with leaf senescence in Arabidopsis and soybean were incorporated.
. 37 senescence-associated transcription factors (Sen-TFs) ChIP- or DAP-seq data were added.
. New links to plant senescence resource were provided.

Please Cite:

  LSD 3.0: a comprehensive resource for the leaf senescence research community. Nucleic Acids Res 2020. [PMID=31599330]

last update: 16 May 2022