strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name GCF_002086635.1,alsense,324058,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_002086635.1_AMRSEG0001,NZ_MVHD01000001.1,negative,49489-52916,96.59,80.56,,,,,2017/4/11,720.0,, GCF_002086635.1,alsense,324058,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_002086635.1_AMRSEG0002,NZ_MVHD01000013.1,negative,67230-67561,96.23,87.35,,,,,2017/4/11,720.0,, GCF_002086635.1,alsense,324058,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_002086635.1_AMRSEG0003,NZ_MVHD01000015.1,negative,3969-5561,100.0,85.75,,,,,2017/4/11,720.0,, GCF_002086635.1,alsense,324058,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_002086635.1_AMRSEG0004,NZ_MVHD01000023.1,negative,44456-45142,100.0,90.54,,,,,2017/4/11,720.0,, GCF_002086635.1,alsense,324058,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_002086635.1_AMRSEG0005,NZ_MVHD01000043.1,positive,17818-18362,99.82,80.18,,,,,2017/4/11,720.0,,