strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name GCF_000613245.1,asiaticum,1790,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_000613245.1_AMRSEG0001,NZ_HG964936.1,positive,560023-563433,97.25,81.21,,,,,2014/3/26,2.0,, GCF_000613245.1,asiaticum,1790,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_000613245.1_AMRSEG0002,NZ_HG964936.1,positive,894989-895675,100.0,90.83,,,,,2014/3/26,2.0,, GCF_000613245.1,asiaticum,1790,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_000613245.1_AMRSEG0003,NZ_HG964936.1,positive,1611039-1612630,99.94,83.79,,,,,2014/3/26,2.0,, GCF_000613245.1,asiaticum,1790,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_000613245.1_AMRSEG0004,NZ_HG964937.1,negative,1233601-1233915,91.3,89.21,,,,,2014/3/26,2.0,, GCF_002086545.1,asiaticum,1790,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_002086545.1_AMRSEG0001,NZ_MVHI01000003.1,positive,117543-120953,97.25,81.21,,,,,2017/4/11,2.0,, GCF_002086545.1,asiaticum,1790,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_002086545.1_AMRSEG0002,NZ_MVHI01000011.1,positive,69522-70208,100.0,90.83,,,,,2017/4/11,2.0,, GCF_002086545.1,asiaticum,1790,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_002086545.1_AMRSEG0003,NZ_MVHI01000018.1,positive,110855-112446,99.94,83.79,,,,,2017/4/11,2.0,, GCF_002086545.1,asiaticum,1790,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_002086545.1_AMRSEG0004,NZ_MVHI01000033.1,negative,42561-42875,91.3,89.21,,,,,2017/4/11,2.0,, SRR7800710,asiaticum,1790,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR7800710_AMRSEG0001,NODE_2_length_370524_cov_58.446228,negative,305353-306039,100.0,90.68,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,United States of America,2016/1/1,,, SRR7800710,asiaticum,1790,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR7800710_AMRSEG0002,NODE_35_length_55714_cov_52.427701,positive,16916-17230,91.3,89.52,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,United States of America,2016/1/1,,, SRR7800710,asiaticum,1790,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR7800710_AMRSEG0003,NODE_4_length_244774_cov_59.762888,negative,116870-120280,97.31,81.08,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,United States of America,2016/1/1,,, SRR7800710,asiaticum,1790,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR7800710_AMRSEG0004,NODE_5_length_224028_cov_57.073485,positive,216803-218394,99.94,83.67,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,United States of America,2016/1/1,,,