strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCF_000612725.1,austroafricanum,39687,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_000612725.1_AMRSEG0001,NZ_HG964451.1,negative,89095-89781,100.0,86.32,,,,,2014/3/26,155.0,,
GCF_000612725.1,austroafricanum,39687,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_000612725.1_AMRSEG0002,NZ_HG964451.1,negative,628294-631773,99.0,81.34,,,,,2014/3/26,155.0,,
GCF_000612725.1,austroafricanum,39687,tap,ARO:3000343,antibiotic efflux,Mycolicibacterium fortuitum,tetracycline antibiotic,"Efflux pump proteins contained within Mycobacterial genomes which confer resistance to a number of different antibiotics including aminoglycosides, and tetracyclines.",GCF_000612725.1_AMRSEG0003,NZ_HG964452.1,positive,63789-64989,97.64,81.35,,,,,2014/3/26,155.0,,
GCF_000612725.1,austroafricanum,39687,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_000612725.1_AMRSEG0004,NZ_HG964456.1,negative,364476-364807,96.23,89.46,,,,,2014/3/26,155.0,,
GCF_016919645.1,austroafricanum,39687,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_016919645.1_AMRSEG0001,NZ_CP070380.1,positive,1050497-1053976,99.0,81.39,,,,,2021/2/23,,,
GCF_016919645.1,austroafricanum,39687,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_016919645.1_AMRSEG0002,NZ_CP070380.1,positive,1595166-1595852,100.0,86.46,,,,,2021/2/23,,,
GCF_016919645.1,austroafricanum,39687,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_016919645.1_AMRSEG0003,NZ_CP070380.1,positive,3410297-3410628,96.23,89.46,,,,,2021/2/23,,,
GCF_016919645.1,austroafricanum,39687,tap,ARO:3000343,antibiotic efflux,Mycolicibacterium fortuitum,tetracycline antibiotic,"Efflux pump proteins contained within Mycobacterial genomes which confer resistance to a number of different antibiotics including aminoglycosides, and tetracyclines.",GCF_016919645.1_AMRSEG0004,NZ_CP070380.1,positive,4584849-4586052,97.89,81.56,,,,,2021/2/23,,,