strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
ERR2331018,basiliense,2094119,mfpA,ARO:3003035,antibiotic target protection,Mycobacterium tuberculosis H37Rv,fluoroquinolone antibiotic,mfpA is a qnr homolog and a pentapeptide repeat protein that confers resistance to fluoroquinolones in Mycolicibacterium smegmatis.,ERR2331018_AMRSEG0001,NODE_120_length_9108_cov_32.181758,positive,6544-7093,99.46,80.0,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:BAL,Switzerland,2013/1/1,,,
ERR2331018,basiliense,2094119,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,ERR2331018_AMRSEG0002,NODE_23_length_68263_cov_31.214311,negative,66468-66782,91.3,84.13,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:BAL,Switzerland,2013/1/1,,,
ERR2331018,basiliense,2094119,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",ERR2331018_AMRSEG0003,NODE_2_length_180002_cov_32.075937,negative,170143-173553,96.7,80.05,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:BAL,Switzerland,2013/1/1,,,
ERR2331018,basiliense,2094119,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,ERR2331018_AMRSEG0004,NODE_50_length_38338_cov_30.593834,negative,36880-37566,100.0,89.96,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:BAL,Switzerland,2013/1/1,,,
ERR2331018,basiliense,2094119,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,ERR2331018_AMRSEG0005,NODE_8_length_109442_cov_31.873550,positive,12275-13867,99.94,87.14,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:BAL,Switzerland,2013/1/1,,,
ERR2331022,basiliense,2094119,mfpA,ARO:3003035,antibiotic target protection,Mycobacterium tuberculosis H37Rv,fluoroquinolone antibiotic,mfpA is a qnr homolog and a pentapeptide repeat protein that confers resistance to fluoroquinolones in Mycolicibacterium smegmatis.,ERR2331022_AMRSEG0001,NODE_124_length_9015_cov_31.910523,negative,2013-2562,99.46,80.0,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:BAL,Switzerland,2017/1/1,,,
ERR2331022,basiliense,2094119,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,ERR2331022_AMRSEG0002,NODE_28_length_64865_cov_28.962887,negative,33338-33652,91.3,84.13,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:BAL,Switzerland,2017/1/1,,,
ERR2331022,basiliense,2094119,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",ERR2331022_AMRSEG0003,NODE_2_length_181306_cov_27.541124,negative,170143-173553,96.7,80.05,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:BAL,Switzerland,2017/1/1,,,
ERR2331022,basiliense,2094119,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,ERR2331022_AMRSEG0004,NODE_44_length_36931_cov_28.243599,negative,35451-36137,100.0,89.96,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:BAL,Switzerland,2017/1/1,,,
ERR2331022,basiliense,2094119,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,ERR2331022_AMRSEG0005,NODE_8_length_110691_cov_28.016894,negative,95577-97169,99.94,87.14,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:BAL,Switzerland,2017/1/1,,,