strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCF_000222105.3,colombiense,339268,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_000222105.3_AMRSEG0001,NZ_AFVW02000001.1,negative,15946-19367,97.36,81.77,,,,,2012/9/11,124.0,,
GCF_000222105.3,colombiense,339268,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_000222105.3_AMRSEG0002,NZ_AFVW02000002.1,negative,902957-903277,93.04,87.23,,,,,2012/9/11,124.0,,
GCF_000222105.3,colombiense,339268,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_000222105.3_AMRSEG0003,NZ_AFVW02000004.1,negative,340060-340746,100.0,88.65,,,,,2012/9/11,124.0,,
GCF_000222105.3,colombiense,339268,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_000222105.3_AMRSEG0004,NZ_AFVW02000006.1,negative,513274-514889,99.87,83.73,,,,,2012/9/11,124.0,,