strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name GCF_000613185.1,cosmeticum,258533,lfrA,ARO:3003967,antibiotic efflux,Mycolicibacterium smegmatis MC2 155,fluoroquinolone antibiotic,lfrA is involved in the active efflux of quinolones and is found in Mycobacteroides abscessus.,GCF_000613185.1_AMRSEG0001,NZ_CCBB010000001.1,positive,2512381-2513843,96.3,80.87,,,,,2014/3/20,149.0,, GCF_000613185.1,cosmeticum,258533,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_000613185.1_AMRSEG0002,NZ_CCBB010000002.1,negative,540145-540476,96.23,86.14,,,,,2014/3/20,149.0,, GCF_000613185.1,cosmeticum,258533,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_000613185.1_AMRSEG0003,NZ_CCBB010000003.1,positive,637069-640538,98.88,81.13,,,,,2014/3/20,149.0,, GCF_000613185.1,cosmeticum,258533,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_000613185.1_AMRSEG0004,NZ_CCBB010000003.1,positive,1113608-1114287,98.98,86.62,,,,,2014/3/20,149.0,,