strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
DRR161214,florentinum,292462,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",DRR161214_AMRSEG0001,NODE_1_length_1499181_cov_18.627476,negative,45929-49315,96.68,81.2,,,,,,676.0,,
DRR161214,florentinum,292462,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,DRR161214_AMRSEG0002,NODE_1_length_1499181_cov_18.627476,positive,477297-477841,99.82,82.02,,,,,,676.0,,
DRR161214,florentinum,292462,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,DRR161214_AMRSEG0003,NODE_4_length_562284_cov_18.850607,positive,160266-161869,99.94,84.41,,,,,,676.0,,
DRR161214,florentinum,292462,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,DRR161214_AMRSEG0004,NODE_5_length_518800_cov_18.250753,negative,233448-233779,96.23,88.25,,,,,,676.0,,
DRR161214,florentinum,292462,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,DRR161214_AMRSEG0005,NODE_8_length_224108_cov_18.846906,negative,76182-76868,100.0,88.5,,,,,,676.0,,
DRR161214,florentinum,292462,mfpA,ARO:3003035,antibiotic target protection,Mycobacterium tuberculosis H37Rv,fluoroquinolone antibiotic,mfpA is a qnr homolog and a pentapeptide repeat protein that confers resistance to fluoroquinolones in Mycolicibacterium smegmatis.,DRR161214_AMRSEG0006,NODE_8_length_224108_cov_18.846906,negative,210480-211013,96.74,81.46,,,,,,676.0,,
GCF_002101635.1,florentinum,292462,mfpA,ARO:3003035,antibiotic target protection,Mycobacterium tuberculosis H37Rv,fluoroquinolone antibiotic,mfpA is a qnr homolog and a pentapeptide repeat protein that confers resistance to fluoroquinolones in Mycolicibacterium smegmatis.,GCF_002101635.1_AMRSEG0001,NZ_LQOV01000004.1,positive,13110-13643,96.74,81.46,,,,,2017/4/20,676.0,,
GCF_002101635.1,florentinum,292462,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_002101635.1_AMRSEG0002,NZ_LQOV01000004.1,positive,147255-147941,100.0,88.5,,,,,2017/4/20,676.0,,
GCF_002101635.1,florentinum,292462,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_002101635.1_AMRSEG0003,NZ_LQOV01000006.1,positive,284959-285290,96.23,88.25,,,,,2017/4/20,676.0,,
GCF_002101635.1,florentinum,292462,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_002101635.1_AMRSEG0004,NZ_LQOV01000015.1,negative,496295-496839,99.82,82.02,,,,,2017/4/20,676.0,,
GCF_002101635.1,florentinum,292462,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_002101635.1_AMRSEG0005,NZ_LQOV01000015.1,positive,924912-928298,96.68,81.2,,,,,2017/4/20,676.0,,
GCF_002101635.1,florentinum,292462,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_002101635.1_AMRSEG0006,NZ_LQOV01000034.1,positive,525160-526763,99.94,84.41,,,,,2017/4/20,676.0,,