strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCA_000521195.1,gastri,1777,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCA_000521195.1_AMRSEG0001,AZYN01000245.1,positive,8180-8487,89.28,88.31,,,,,2014/1/16,139.0,,
GCA_000521195.1,gastri,1777,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCA_000521195.1_AMRSEG0002,AZYN01000274.1,positive,2950-6375,97.13,80.18,,,,,2014/1/16,139.0,,
GCA_000521195.1,gastri,1777,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCA_000521195.1_AMRSEG0003,AZYN01000330.1,negative,16858-17403,100.0,83.15,,,,,2014/1/16,139.0,,
GCA_000521195.1,gastri,1777,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCA_000521195.1_AMRSEG0004,AZYN01000476.1,positive,17117-17803,100.0,89.96,,,,,2014/1/16,139.0,,
SRR12599236,gastri,1777,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,SRR12599236_AMRSEG0001,NODE_113_length_16601_cov_51.008103,positive,15709-16254,100.0,83.88,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Australia,,570.0,,
SRR12599236,gastri,1777,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR12599236_AMRSEG0002,NODE_15_length_83088_cov_63.203059,positive,75355-75662,89.28,88.31,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Australia,,570.0,,
SRR12599236,gastri,1777,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR12599236_AMRSEG0003,NODE_58_length_39177_cov_48.930102,positive,35632-37220,99.69,85.47,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Australia,,570.0,,
SRR12599236,gastri,1777,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR12599236_AMRSEG0004,NODE_70_length_35218_cov_52.231404,negative,14634-15320,100.0,89.81,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Australia,,570.0,,
SRR12599249,gastri,1777,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,SRR12599249_AMRSEG0001,NODE_112_length_17352_cov_53.456417,negative,349-894,100.0,83.88,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Australia,,570.0,,
SRR12599249,gastri,1777,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR12599249_AMRSEG0002,NODE_15_length_82096_cov_60.700011,negative,6435-6742,89.28,88.31,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Australia,,570.0,,
SRR12599249,gastri,1777,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR12599249_AMRSEG0003,NODE_57_length_39300_cov_54.014119,negative,1982-3570,99.69,85.47,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Australia,,570.0,,
SRR12599249,gastri,1777,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR12599249_AMRSEG0004,NODE_71_length_35089_cov_57.279021,negative,14634-15320,100.0,89.81,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Australia,,570.0,,
SRR12599316,gastri,1777,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR12599316_AMRSEG0001,NODE_114_length_12618_cov_44.455516,negative,2001-3589,99.69,85.53,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Switzerland,,570.0,,
SRR12599316,gastri,1777,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,SRR12599316_AMRSEG0002,NODE_15_length_75132_cov_51.146465,negative,59087-59632,100.0,83.88,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Switzerland,,570.0,,
SRR12599316,gastri,1777,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR12599316_AMRSEG0003,NODE_28_length_64313_cov_47.710148,positive,37154-37461,89.28,88.31,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Switzerland,,570.0,,
SRR12599316,gastri,1777,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR12599316_AMRSEG0004,NODE_79_length_25142_cov_48.914231,negative,13139-13825,100.0,89.81,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Switzerland,,570.0,,
SRR12599330,gastri,1777,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR12599330_AMRSEG0001,NODE_15_length_96459_cov_44.897911,positive,46457-49882,97.13,80.18,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Canada,,139.0,,
SRR12599330,gastri,1777,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR12599330_AMRSEG0002,NODE_20_length_87465_cov_43.060227,negative,84867-85553,100.0,89.96,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Canada,,139.0,,
SRR12599330,gastri,1777,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,SRR12599330_AMRSEG0003,NODE_27_length_79154_cov_43.728073,positive,13452-13997,100.0,83.15,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Canada,,139.0,,
SRR12599330,gastri,1777,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR12599330_AMRSEG0004,NODE_63_length_29535_cov_36.699613,positive,1789-2096,89.28,88.31,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Canada,,139.0,,
SRR12599330,gastri,1777,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR12599330_AMRSEG0005,NODE_86_length_18318_cov_39.665023,positive,9143-10731,99.69,85.72,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,Canada,,139.0,,