strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCF_001021435.1,haemophilum,29311,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_001021435.1_AMRSEG0001,NZ_LDPS01000003.1,negative,36074-39505,97.02,80.27,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,29.0,,
GCF_001021435.1,haemophilum,29311,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_001021435.1_AMRSEG0002,NZ_LDPS01000011.1,negative,27882-28568,100.0,91.85,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,29.0,,
GCF_001021435.1,haemophilum,29311,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_001021435.1_AMRSEG0003,NZ_LDPS01000013.1,negative,29153-30741,99.75,85.36,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,29.0,,
GCF_001021435.1,haemophilum,29311,AAC(2')-Ie,ARO:3002527,antibiotic inactivation,Mycobacterium leprae,aminoglycoside antibiotic,AAC(2')-Ie is a chromosomal-encoded aminoglycoside acetyltransferase in M. leprae.,GCF_001021435.1_AMRSEG0004,NZ_LDPS01000017.1,positive,59703-60237,97.45,88.78,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,29.0,,
GCF_001021435.1,haemophilum,29311,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_001021435.1_AMRSEG0005,NZ_LDPS01000023.1,negative,31822-32136,91.3,86.98,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,29.0,,
GCF_001021435.1,haemophilum,29311,tet(C),ARO:3000167,antibiotic efflux,Aeromonas salmonicida,tetracycline antibiotic,Tet(C) is a tetracycline efflux pump found in many species of Gram-negative bacteria. It is typically found in plasmid DNA.,GCF_001021435.1_AMRSEG0006,NZ_LDPS01000043.1,negative,627-1817,100.0,100.0,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,29.0,,
GCF_001021485.1,haemophilum,29311,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_001021485.1_AMRSEG0001,NZ_LDPQ01000001.1,negative,405193-405879,100.0,91.85,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,29.0,,
GCF_001021485.1,haemophilum,29311,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_001021485.1_AMRSEG0002,NZ_LDPQ01000002.1,negative,36074-39505,97.02,80.27,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,29.0,,
GCF_001021485.1,haemophilum,29311,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_001021485.1_AMRSEG0003,NZ_LDPQ01000013.1,negative,29153-30741,99.75,85.36,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,29.0,,
GCF_001021485.1,haemophilum,29311,AAC(2')-Ie,ARO:3002527,antibiotic inactivation,Mycobacterium leprae,aminoglycoside antibiotic,AAC(2')-Ie is a chromosomal-encoded aminoglycoside acetyltransferase in M. leprae.,GCF_001021485.1_AMRSEG0004,NZ_LDPQ01000018.1,negative,30568-31102,97.45,88.78,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,29.0,,
GCF_001021485.1,haemophilum,29311,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_001021485.1_AMRSEG0005,NZ_LDPQ01000026.1,negative,31822-32136,91.3,86.98,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,29.0,,