strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
DRR260918,heckeshornense,110505,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,DRR260918_AMRSEG0001,NODE_38_length_41807_cov_18.165724,positive,37717-38403,100.0,88.21,Homo sapiens,Homo sapiens,Homo sapiens_no_further_detail,Germany,1994/1/1,151.0,,
DRR260918,heckeshornense,110505,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",DRR260918_AMRSEG0002,NODE_81_length_18566_cov_20.361347,positive,11057-14475,97.16,80.54,Homo sapiens,Homo sapiens,Homo sapiens_no_further_detail,Germany,1994/1/1,151.0,,
DRR260918,heckeshornense,110505,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,DRR260918_AMRSEG0003,NODE_88_length_16752_cov_18.097609,positive,4692-5007,91.59,85.76,Homo sapiens,Homo sapiens,Homo sapiens_no_further_detail,Germany,1994/1/1,151.0,,
GCF_001077755.1,heckeshornense,110505,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_001077755.1_AMRSEG0001,NZ_LFOF01000004.1,negative,141073-144491,97.16,80.54,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/7/14,151.0,,
GCF_001077755.1,heckeshornense,110505,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_001077755.1_AMRSEG0002,NZ_LFOF01000034.1,negative,3397-4083,100.0,88.21,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/7/14,151.0,,
GCF_001077755.1,heckeshornense,110505,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_001077755.1_AMRSEG0003,NZ_LFOF01000058.1,negative,11753-12068,91.59,85.76,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/7/14,151.0,,
GCF_016861545.1,heckeshornense,110505,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_016861545.1_AMRSEG0001,NZ_AP024310.1,negative,2371837-2372152,91.59,86.08,,,,,2021/1/22,151.0,,
GCF_016861545.1,heckeshornense,110505,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_016861545.1_AMRSEG0002,NZ_AP024310.1,negative,3736694-3737380,100.0,88.21,,,,,2021/1/22,151.0,,
GCF_016861545.1,heckeshornense,110505,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_016861545.1_AMRSEG0003,NZ_AP024310.1,negative,4032879-4036297,97.16,80.54,,,,,2021/1/22,151.0,,