strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
DRR161216,heidelbergense,53376,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,DRR161216_AMRSEG0001,NODE_11_length_168463_cov_22.069115,positive,109686-110218,97.25,81.5,,,,,,728.0,,
DRR161216,heidelbergense,53376,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,DRR161216_AMRSEG0002,NODE_17_length_123895_cov_21.619452,negative,21035-21721,100.0,90.1,,,,,,728.0,,
DRR161216,heidelbergense,53376,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",DRR161216_AMRSEG0003,NODE_18_length_123799_cov_21.486964,positive,61303-64743,97.33,81.1,,,,,,728.0,,
DRR161216,heidelbergense,53376,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,DRR161216_AMRSEG0004,NODE_4_length_294247_cov_23.869663,negative,136123-136463,97.97,84.16,,,,,,728.0,,
DRR161216,heidelbergense,53376,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,DRR161216_AMRSEG0005,NODE_7_length_244794_cov_21.136791,negative,186037-187628,99.94,86.24,,,,,,728.0,,
GCF_002086215.1,heidelbergense,53376,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_002086215.1_AMRSEG0001,NZ_MVHR01000003.1,negative,107143-107483,97.97,84.16,,,,,2017/4/11,728.0,,
GCF_002086215.1,heidelbergense,53376,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_002086215.1_AMRSEG0002,NZ_MVHR01000004.1,negative,186247-187838,99.94,86.24,,,,,2017/4/11,728.0,,
GCF_002086215.1,heidelbergense,53376,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_002086215.1_AMRSEG0003,NZ_MVHR01000006.1,negative,77100-77786,100.0,90.1,,,,,2017/4/11,728.0,,
GCF_002086215.1,heidelbergense,53376,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_002086215.1_AMRSEG0004,NZ_MVHR01000012.1,negative,59254-62694,97.33,81.1,,,,,2017/4/11,728.0,,
GCF_002086215.1,heidelbergense,53376,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_002086215.1_AMRSEG0005,NZ_MVHR01000027.1,negative,58260-58792,97.25,81.5,,,,,2017/4/11,728.0,,