strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCF_001021505.1,heraklionense,512402,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_001021505.1_AMRSEG0001,NZ_LDPO01000001.1,negative,662616-666050,97.02,81.4,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,94.0,,
GCF_001021505.1,heraklionense,512402,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_001021505.1_AMRSEG0002,NZ_LDPO01000002.1,positive,145723-146054,96.23,87.35,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,94.0,,
GCF_001021505.1,heraklionense,512402,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_001021505.1_AMRSEG0003,NZ_LDPO01000005.1,positive,197916-198602,100.0,86.9,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum,United States of America,2015/6/8,94.0,,
SRR14027494,heraklionense,512402,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR14027494_AMRSEG0001,NODE_2_length_151977_cov_108.558625,negative,2131-2817,100.0,86.61,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,India,2017/12/1,,,
SRR14027494,heraklionense,512402,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR14027494_AMRSEG0002,NODE_40_length_37701_cov_128.898640,negative,32031-35456,96.7,81.18,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,India,2017/12/1,,,
SRR14027494,heraklionense,512402,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR14027494_AMRSEG0003,NODE_9_length_87112_cov_119.105573,negative,67352-67683,96.23,85.84,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary:sputum,India,2017/12/1,,,