strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCF_001722355.1,holsaticum,152142,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_001722355.1_AMRSEG0001,NZ_MIGZ01000002.1,positive,65276-68648,96.13,81.42,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,558.0,,
GCF_001722355.1,holsaticum,152142,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_001722355.1_AMRSEG0002,NZ_MIGZ01000019.1,positive,40336-40655,92.75,86.88,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,558.0,,
GCF_001722355.1,holsaticum,152142,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_001722355.1_AMRSEG0003,NZ_MIGZ01000179.1,positive,9939-10625,100.0,86.32,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,558.0,,
GCF_001722355.1,holsaticum,152142,AAC(2')-Ib,ARO:3002524,antibiotic inactivation,Mycolicibacterium fortuitum,aminoglycoside antibiotic,AAC(2')-Ib is a chromosomal-encoded aminoglycoside acetyltransferase in Mycolicibacterium fortuitum and A. baumannii.,GCF_001722355.1_AMRSEG0004,NZ_MIGZ01000215.1,positive,2329-2870,92.01,80.11,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,558.0,,
GCF_001722355.1,holsaticum,152142,sul1,ARO:3000410,antibiotic target replacement,Vibrio fluvialis,sulfonamide antibiotic,Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons.,GCF_001722355.1_AMRSEG0005,NZ_MIGZ01000289.1,negative,1199-2038,100.0,100.0,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,558.0,,
GCF_001722355.1,holsaticum,152142,aadA9,ARO:3002609,antibiotic inactivation,Corynebacterium sp. L2-79-05,aminoglycoside antibiotic,aadA9 is a plasmid-encoded aminoglycoside nucleotidyltransferase gene in C. glutamicum.,GCF_001722355.1_AMRSEG0006,NZ_MIGZ01000289.1,negative,2543-3442,100.0,100.0,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,558.0,,
GCF_001722355.1,holsaticum,152142,tet(33),ARO:3000478,antibiotic efflux,Corynebacterium glutamicum,tetracycline antibiotic,"Tet33 is a tetracycline efflux pump found in Gram-positive bacteria, including Arthrobacter and Corynebacterium.",GCF_001722355.1_AMRSEG0007,NZ_MIGZ01000299.1,negative,785-2008,100.0,100.0,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,558.0,,