strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCA_001632885.1,innocens,2341083,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCA_001632885.1_AMRSEG0001,LWCK01000011.1,negative,89854-90540,100.0,90.39,,,,,2016/4/27,95.0,,
GCA_001632885.1,innocens,2341083,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCA_001632885.1_AMRSEG0002,LWCK01000083.1,positive,15841-19263,97.13,80.37,,,,,2016/4/27,95.0,,
GCA_001632885.1,innocens,2341083,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCA_001632885.1_AMRSEG0003,LWCK01000094.1,positive,8049-8603,100.0,81.44,,,,,2016/4/27,95.0,,
GCA_001632885.1,innocens,2341083,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCA_001632885.1_AMRSEG0004,LWCK01000120.1,negative,29590-31178,99.69,85.79,,,,,2016/4/27,95.0,,
GCA_001632885.1,innocens,2341083,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCA_001632885.1_AMRSEG0005,LWCK01000154.1,positive,75498-75805,89.28,87.66,,,,,2016/4/27,95.0,,
GCA_001632905.1,innocens,2341083,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCA_001632905.1_AMRSEG0001,LWCH01000133.1,positive,42546-45968,97.13,80.51,,,,,2016/4/27,417.0,,
GCA_001632905.1,innocens,2341083,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCA_001632905.1_AMRSEG0002,LWCH01000229.1,positive,40044-40351,89.28,87.66,,,,,2016/4/27,417.0,,
GCA_001632905.1,innocens,2341083,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCA_001632905.1_AMRSEG0003,LWCH01000284.1,negative,965-2553,99.69,86.29,,,,,2016/4/27,417.0,,
GCA_001632905.1,innocens,2341083,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCA_001632905.1_AMRSEG0004,LWCH01000306.1,negative,15658-16344,100.0,90.25,,,,,2016/4/27,417.0,,
GCA_001632905.1,innocens,2341083,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCA_001632905.1_AMRSEG0005,LWCH01000335.1,positive,8021-8575,100.0,81.62,,,,,2016/4/27,417.0,,
GCF_900566055.1,innocens,2341083,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_900566055.1_AMRSEG0001,NZ_UPHQ01000009.1,negative,12252-12806,100.0,81.62,,,,,2018/11/1,417.0,,
GCF_900566055.1,innocens,2341083,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_900566055.1_AMRSEG0002,NZ_UPHQ01000033.1,positive,42663-46085,97.13,80.54,,,,,2018/11/1,417.0,,
GCF_900566055.1,innocens,2341083,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_900566055.1_AMRSEG0003,NZ_UPHQ01000046.1,positive,12578-13264,100.0,90.25,,,,,2018/11/1,417.0,,
GCF_900566055.1,innocens,2341083,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_900566055.1_AMRSEG0004,NZ_UPHQ01000070.1,positive,47607-49195,99.69,86.29,,,,,2018/11/1,417.0,,
GCF_900566055.1,innocens,2341083,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_900566055.1_AMRSEG0005,NZ_UPHQ01000140.1,positive,40072-40379,89.28,87.66,,,,,2018/11/1,417.0,,