strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCA_002024965.1,intermedium,28445,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCA_002024965.1_AMRSEG0001,MIJC01000005.1,negative,68161-68847,100.0,90.39,,,,,2017/3/10,552.0,,
GCA_002024965.1,intermedium,28445,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCA_002024965.1_AMRSEG0002,MIJC01000013.1,positive,16254-16569,91.59,84.81,,,,,2017/3/10,552.0,,
GCA_002024965.1,intermedium,28445,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCA_002024965.1_AMRSEG0003,MIJC01000019.1,positive,30529-33950,97.28,80.3,,,,,2017/3/10,552.0,,
GCA_002024965.1,intermedium,28445,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCA_002024965.1_AMRSEG0004,MIJC01000080.1,negative,23468-23998,97.25,80.04,,,,,2017/3/10,552.0,,
GCA_002024965.1,intermedium,28445,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCA_002024965.1_AMRSEG0005,MIJC01000139.1,negative,5639-7231,99.87,84.45,,,,,2017/3/10,552.0,,
GCF_001722345.1,intermedium,28445,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_001722345.1_AMRSEG0001,NZ_MIHB01000001.1,positive,273784-275376,99.87,84.45,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,552.0,,
GCF_001722345.1,intermedium,28445,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_001722345.1_AMRSEG0002,NZ_MIHB01000013.1,positive,16053-16739,100.0,90.39,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,552.0,,
GCF_001722345.1,intermedium,28445,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_001722345.1_AMRSEG0003,NZ_MIHB01000028.1,positive,16393-16708,91.59,84.81,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,552.0,,
GCF_001722345.1,intermedium,28445,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_001722345.1_AMRSEG0004,NZ_MIHB01000037.1,negative,30613-34034,97.28,80.3,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,552.0,,
GCF_001722345.1,intermedium,28445,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_001722345.1_AMRSEG0005,NZ_MIHB01000056.1,positive,12012-12542,97.25,80.04,Homo sapiens,Homo sapiens: extrapulmonary,Homo sapiens:extrapulmonary :blood,United States of America,2016/9/9,552.0,,
GCF_002086275.1,intermedium,28445,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_002086275.1_AMRSEG0001,NZ_MVHT01000002.1,positive,34654-35340,100.0,90.39,,,,,2017/4/11,552.0,,
GCF_002086275.1,intermedium,28445,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_002086275.1_AMRSEG0002,NZ_MVHT01000005.1,positive,13712-15304,99.87,84.45,,,,,2017/4/11,552.0,,
GCF_002086275.1,intermedium,28445,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_002086275.1_AMRSEG0003,NZ_MVHT01000021.1,negative,33132-33662,97.25,80.04,,,,,2017/4/11,552.0,,
GCF_002086275.1,intermedium,28445,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_002086275.1_AMRSEG0004,NZ_MVHT01000025.1,negative,56526-56841,91.59,84.81,,,,,2017/4/11,552.0,,
GCF_002086275.1,intermedium,28445,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_002086275.1_AMRSEG0005,NZ_MVHT01000034.1,positive,29938-33359,97.28,80.3,,,,,2017/4/11,552.0,,