strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name DRR161209,kubicae,120959,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,DRR161209_AMRSEG0001,NODE_16_length_147443_cov_20.922262,positive,98841-99527,100.0,90.39,,,,,,681.0,, DRR161209,kubicae,120959,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,DRR161209_AMRSEG0002,NODE_1_length_340849_cov_20.693790,negative,170924-171468,99.27,81.35,,,,,,681.0,, DRR161209,kubicae,120959,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,DRR161209_AMRSEG0003,NODE_2_length_300617_cov_20.652801,positive,91293-92885,100.0,85.62,,,,,,681.0,, DRR161209,kubicae,120959,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",DRR161209_AMRSEG0004,NODE_43_length_24956_cov_21.249669,negative,5994-9409,97.33,81.16,,,,,,681.0,, DRR161209,kubicae,120959,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,DRR161209_AMRSEG0005,NODE_49_length_16832_cov_19.691812,positive,1623-1936,91.01,86.31,,,,,,681.0,, GCF_002101745.1,kubicae,120959,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_002101745.1_AMRSEG0001,NZ_LQPD01000014.1,positive,98855-99541,100.0,90.39,,,,,2017/4/20,681.0,, GCF_002101745.1,kubicae,120959,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_002101745.1_AMRSEG0002,NZ_LQPD01000019.1,positive,78094-81509,97.33,81.16,,,,,2017/4/20,681.0,, GCF_002101745.1,kubicae,120959,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_002101745.1_AMRSEG0003,NZ_LQPD01000035.1,negative,14911-15224,91.01,86.31,,,,,2017/4/20,681.0,, GCF_002101745.1,kubicae,120959,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_002101745.1_AMRSEG0004,NZ_LQPD01000080.1,positive,90832-92424,100.0,85.62,,,,,2017/4/20,681.0,, GCF_002101745.1,kubicae,120959,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_002101745.1_AMRSEG0005,NZ_LQPD01000109.1,positive,38274-38818,99.27,81.35,,,,,2017/4/20,681.0,, GCF_015689175.1,kubicae,120959,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_015689175.1_AMRSEG0001,NZ_CP065047.1,negative,637856-638400,99.27,81.35,,,,,2020/11/25,681.0,, GCF_015689175.1,kubicae,120959,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_015689175.1_AMRSEG0002,NZ_CP065047.1,positive,1066538-1069953,97.33,81.16,,,,,2020/11/25,681.0,, GCF_015689175.1,kubicae,120959,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_015689175.1_AMRSEG0003,NZ_CP065047.1,positive,1368409-1369095,100.0,90.39,,,,,2020/11/25,681.0,, GCF_015689175.1,kubicae,120959,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_015689175.1_AMRSEG0004,NZ_CP065047.1,positive,1971723-1973315,100.0,85.62,,,,,2020/11/25,681.0,, GCF_015689175.1,kubicae,120959,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_015689175.1_AMRSEG0005,NZ_CP065047.1,positive,3167076-3167389,91.01,86.31,,,,,2020/11/25,681.0,,