strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
DRR161229,litorale,758802,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",DRR161229_AMRSEG0001,NODE_5_length_483921_cov_17.742344,negative,79541-82942,96.59,81.27,,,,,,856.0,,
DRR161229,litorale,758802,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,DRR161229_AMRSEG0002,NODE_6_length_478153_cov_21.029967,negative,193066-193397,96.23,91.57,,,,,,856.0,,
DRR161229,litorale,758802,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,DRR161229_AMRSEG0003,NODE_9_length_269592_cov_18.769876,negative,261180-261866,100.0,85.01,,,,,,856.0,,
DRR236240,litorale,758802,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,DRR236240_AMRSEG0001,NODE_1_length_219114_cov_29.064099,positive,195407-195738,96.23,90.36,Homo sapiens,Homo sapiens,Homo sapiens_no_further_detail,Japan,2018/1/1,,,
DRR236240,litorale,758802,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",DRR236240_AMRSEG0002,NODE_38_length_45596_cov_31.983836,negative,37177-40578,96.62,81.06,Homo sapiens,Homo sapiens,Homo sapiens_no_further_detail,Japan,2018/1/1,,,
DRR236240,litorale,758802,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,DRR236240_AMRSEG0003,NODE_5_length_182844_cov_28.671284,negative,72688-73374,100.0,84.72,Homo sapiens,Homo sapiens,Homo sapiens_no_further_detail,Japan,2018/1/1,,,
GCA_002007745.1,litorale,758802,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCA_002007745.1_AMRSEG0001,CP019882.1,positive,1044037-1047407,96.1,82.0,,,,,2017/2/28,747.0,,
GCA_002007745.1,litorale,758802,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCA_002007745.1_AMRSEG0002,CP019882.1,negative,2527338-2527669,96.23,87.65,,,,,2017/2/28,747.0,,
GCA_002007745.1,litorale,758802,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCA_002007745.1_AMRSEG0003,CP019882.1,negative,4463980-4464666,100.0,87.48,,,,,2017/2/28,747.0,,