strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCA_001907615.1,mageritense,53462,vanR_in_vanO_cl,ARO:3002930,antibiotic target alteration,Rhodococcus hoagii,glycopeptide antibiotic,"Also known as vanRO, is a vanR variant found in the vanO gene cluster.",GCA_001907615.1_AMRSEG0001,JMHR01000050.1,positive,206979-207644,94.87,84.38,,,,,2016/12/15,564.0,,
GCA_001907615.1,mageritense,53462,AAC(2')-Ib,ARO:3002524,antibiotic inactivation,Mycolicibacterium fortuitum,aminoglycoside antibiotic,AAC(2')-Ib is a chromosomal-encoded aminoglycoside acetyltransferase in Mycolicibacterium fortuitum and A. baumannii.,GCA_001907615.1_AMRSEG0002,JMHR01000067.1,positive,30972-31502,90.31,84.53,,,,,2016/12/15,564.0,,
GCA_001907615.1,mageritense,53462,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCA_001907615.1_AMRSEG0003,JMHR01000097.1,positive,18856-19187,96.23,93.67,,,,,2016/12/15,564.0,,
GCA_001907615.1,mageritense,53462,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCA_001907615.1_AMRSEG0004,JMHR01000155.1,negative,28351-31839,99.11,81.25,,,,,2016/12/15,564.0,,
GCA_001907615.1,mageritense,53462,tet(V),ARO:3000181,antibiotic efflux,Mycolicibacterium smegmatis MC2 155,tetracycline antibiotic,TetV is a tetracycline efflux protein that has been found in Mycolicibacterium smegmatis and Mycolicibacterium fortuitum.,GCA_001907615.1_AMRSEG0005,JMHR01000200.1,positive,41972-43208,97.3,81.24,,,,,2016/12/15,564.0,,
GCA_001907615.1,mageritense,53462,tap,ARO:3000343,antibiotic efflux,Mycolicibacterium fortuitum,tetracycline antibiotic,"Efflux pump proteins contained within Mycobacterial genomes which confer resistance to a number of different antibiotics including aminoglycosides, and tetracyclines.",GCA_001907615.1_AMRSEG0006,JMHR01000202.1,negative,43903-45114,98.54,84.08,,,,,2016/12/15,564.0,,
GCA_001907615.1,mageritense,53462,erm(40),ARO:3004606,antibiotic target alteration,Mycolicibacterium mageritense,macrolide antibiotic;streptogramin antibiotic;lincosamide antibiotic,erm(40) is an adenine RNA methylase and confers intrinsic resistance in Mycobacteria.,GCA_001907615.1_AMRSEG0007,JMHR01000229.1,negative,3908-4663,100.0,97.35,,,,,2016/12/15,564.0,,
GCA_001907615.1,mageritense,53462,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCA_001907615.1_AMRSEG0008,JMHR01000270.1,negative,12471-13157,100.0,85.59,,,,,2016/12/15,564.0,,
GCF_000612825.1,mageritense,53462,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_000612825.1_AMRSEG0001,NZ_CCBF010000001.1,negative,470810-471496,100.0,85.44,,,,,2014/3/31,214.0,,
GCF_000612825.1,mageritense,53462,erm(40),ARO:3004606,antibiotic target alteration,Mycolicibacterium mageritense,macrolide antibiotic;streptogramin antibiotic;lincosamide antibiotic,erm(40) is an adenine RNA methylase and confers intrinsic resistance in Mycobacteria.,GCF_000612825.1_AMRSEG0002,NZ_CCBF010000001.1,positive,661381-662136,100.0,100.0,,,,,2014/3/31,214.0,,
GCF_000612825.1,mageritense,53462,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_000612825.1_AMRSEG0003,NZ_CCBF010000001.1,negative,1011066-1014554,99.11,81.25,,,,,2014/3/31,214.0,,
GCF_000612825.1,mageritense,53462,lfrA,ARO:3003967,antibiotic efflux,Mycolicibacterium smegmatis MC2 155,fluoroquinolone antibiotic,lfrA is involved in the active efflux of quinolones and is found in Mycobacteroides abscessus.,GCF_000612825.1_AMRSEG0004,NZ_CCBF010000001.1,negative,2839653-2841140,98.02,83.06,,,,,2014/3/31,214.0,,
GCF_000612825.1,mageritense,53462,AAC(2')-Ib,ARO:3002524,antibiotic inactivation,Mycolicibacterium fortuitum,aminoglycoside antibiotic,AAC(2')-Ib is a chromosomal-encoded aminoglycoside acetyltransferase in Mycolicibacterium fortuitum and A. baumannii.,GCF_000612825.1_AMRSEG0005,NZ_CCBF010000001.1,negative,3543486-3544016,90.31,84.35,,,,,2014/3/31,214.0,,
GCF_000612825.1,mageritense,53462,vanR_in_vanO_cl,ARO:3002930,antibiotic target alteration,Rhodococcus hoagii,glycopeptide antibiotic,"Also known as vanRO, is a vanR variant found in the vanO gene cluster.",GCF_000612825.1_AMRSEG0006,NZ_CCBF010000001.1,negative,3614801-3615466,94.87,84.53,,,,,2014/3/31,214.0,,
GCF_000612825.1,mageritense,53462,tap,ARO:3000343,antibiotic efflux,Mycolicibacterium fortuitum,tetracycline antibiotic,"Efflux pump proteins contained within Mycobacterial genomes which confer resistance to a number of different antibiotics including aminoglycosides, and tetracyclines.",GCF_000612825.1_AMRSEG0007,NZ_CCBF010000002.1,positive,914778-915989,98.54,84.08,,,,,2014/3/31,214.0,,
GCF_000612825.1,mageritense,53462,tet(V),ARO:3000181,antibiotic efflux,Mycolicibacterium smegmatis MC2 155,tetracycline antibiotic,TetV is a tetracycline efflux protein that has been found in Mycolicibacterium smegmatis and Mycolicibacterium fortuitum.,GCF_000612825.1_AMRSEG0008,NZ_CCBF010000002.1,positive,1104626-1105862,97.3,81.16,,,,,2014/3/31,214.0,,
GCF_000612825.1,mageritense,53462,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_000612825.1_AMRSEG0009,NZ_CCBF010000003.1,negative,260042-260381,98.55,92.94,,,,,2014/3/31,214.0,,