strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCF_001870845.1,malmoense,1780,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_001870845.1_AMRSEG0001,NZ_MOWS01000054.1,negative,23203-26628,96.68,81.42,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum of patient with mycobacteriosis,Russia,2016/11/7,516.0,,
GCF_001870845.1,malmoense,1780,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_001870845.1_AMRSEG0002,NZ_MOWS01000072.1,negative,126150-126465,91.59,88.92,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum of patient with mycobacteriosis,Russia,2016/11/7,516.0,,
GCF_001870845.1,malmoense,1780,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_001870845.1_AMRSEG0003,NZ_MOWS01000078.1,negative,36958-38549,99.94,86.87,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum of patient with mycobacteriosis,Russia,2016/11/7,516.0,,
GCF_001870845.1,malmoense,1780,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_001870845.1_AMRSEG0004,NZ_MOWS01000098.1,negative,38141-38827,100.0,89.67,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum of patient with mycobacteriosis,Russia,2016/11/7,516.0,,
GCF_001870845.1,malmoense,1780,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_001870845.1_AMRSEG0005,NZ_MOWS01000139.1,negative,35827-36371,99.27,83.12,Homo sapiens,Homo sapiens: pulmonary,Homo sapiens:pulmonary :sputum of patient with mycobacteriosis,Russia,2016/11/7,516.0,,
GCF_002086305.1,malmoense,1780,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_002086305.1_AMRSEG0001,NZ_MVHV01000002.1,positive,171048-174473,96.65,81.36,,,,,2017/4/11,730.0,,
GCF_002086305.1,malmoense,1780,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_002086305.1_AMRSEG0002,NZ_MVHV01000005.1,positive,113575-115166,99.94,86.68,,,,,2017/4/11,730.0,,
GCF_002086305.1,malmoense,1780,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,GCF_002086305.1_AMRSEG0003,NZ_MVHV01000010.1,positive,52850-53394,99.27,83.12,,,,,2017/4/11,730.0,,
GCF_002086305.1,malmoense,1780,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_002086305.1_AMRSEG0004,NZ_MVHV01000014.1,negative,126144-126459,91.59,88.92,,,,,2017/4/11,730.0,,
GCF_002086305.1,malmoense,1780,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_002086305.1_AMRSEG0005,NZ_MVHV01000030.1,positive,29971-30657,100.0,89.52,,,,,2017/4/11,730.0,,
SRR6046267,malmoense,1780,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR6046267_AMRSEG0001,NODE_14_length_95860_cov_39.824347,negative,6350-7941,99.94,86.68,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046267,malmoense,1780,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR6046267_AMRSEG0002,NODE_1_length_265852_cov_44.396382,negative,107246-110671,96.65,81.36,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046267,malmoense,1780,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR6046267_AMRSEG0003,NODE_32_length_54045_cov_42.296969,positive,29957-30643,100.0,89.52,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046267,malmoense,1780,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,SRR6046267_AMRSEG0004,NODE_3_length_200567_cov_42.702654,negative,147184-147728,99.27,83.12,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046267,malmoense,1780,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR6046267_AMRSEG0005,NODE_5_length_131207_cov_42.284946,positive,1835-2150,91.59,88.92,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046349,malmoense,1780,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR6046349_AMRSEG0001,NODE_15_length_88434_cov_35.023243,negative,86285-86600,91.59,88.92,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046349,malmoense,1780,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR6046349_AMRSEG0002,NODE_2_length_156860_cov_33.325217,negative,67343-68934,99.94,86.68,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046349,malmoense,1780,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR6046349_AMRSEG0003,NODE_43_length_40309_cov_34.102967,positive,29966-30652,100.0,89.52,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046349,malmoense,1780,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR6046349_AMRSEG0004,NODE_4_length_145635_cov_36.880540,negative,127549-130974,96.65,81.36,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046349,malmoense,1780,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,SRR6046349_AMRSEG0005,NODE_71_length_22238_cov_37.881443,positive,8495-9039,99.27,83.12,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046909,malmoense,1780,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR6046909_AMRSEG0001,NODE_10_length_127101_cov_45.345393,negative,107247-110672,96.65,81.34,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046909,malmoense,1780,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR6046909_AMRSEG0002,NODE_34_length_54012_cov_44.807967,positive,29924-30610,100.0,89.52,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046909,malmoense,1780,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR6046909_AMRSEG0003,NODE_7_length_156902_cov_40.474697,positive,87978-89569,99.94,86.68,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046909,malmoense,1780,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,SRR6046909_AMRSEG0004,NODE_8_length_132751_cov_43.462770,positive,8375-8919,99.27,83.12,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046909,malmoense,1780,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR6046909_AMRSEG0005,NODE_9_length_128441_cov_42.938619,negative,126091-126406,91.59,88.92,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,