strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name GCF_002086335.1,mantenii,560555,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_002086335.1_AMRSEG0001,NZ_MVHW01000001.1,negative,51100-51420,93.04,86.6,,,,,2017/4/11,731.0,, GCF_002086335.1,mantenii,560555,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_002086335.1_AMRSEG0002,NZ_MVHW01000003.1,positive,112591-116015,97.36,81.47,,,,,2017/4/11,731.0,, GCF_002086335.1,mantenii,560555,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_002086335.1_AMRSEG0003,NZ_MVHW01000030.1,negative,37599-38285,100.0,90.25,,,,,2017/4/11,731.0,, GCF_002086335.1,mantenii,560555,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,GCF_002086335.1_AMRSEG0004,NZ_MVHW01000033.1,positive,66232-67823,99.87,85.25,,,,,2017/4/11,731.0,,