strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
DRR161221,monacense,85693,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",DRR161221_AMRSEG0001,NODE_20_length_95708_cov_17.165205,negative,60865-64359,99.11,81.02,,,,,,111.0,,
DRR161221,monacense,85693,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,DRR161221_AMRSEG0002,NODE_28_length_63297_cov_21.977259,positive,28747-29078,96.23,91.27,,,,,,111.0,,
DRR161221,monacense,85693,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,DRR161221_AMRSEG0003,NODE_2_length_414453_cov_18.671109,negative,228622-229308,100.0,85.88,,,,,,111.0,,
DRR161221,monacense,85693,arr-1,ARO:3002846,antibiotic inactivation,Mycolicibacterium smegmatis,rifamycin antibiotic,arr-1 is a chromosome-encoded ribosyltransferase found in Mycolicibacterium smegmatis.,DRR161221_AMRSEG0004,NODE_7_length_337363_cov_20.395440,negative,125688-126099,95.37,81.07,,,,,,111.0,,
GCF_002086655.1,monacense,85693,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_002086655.1_AMRSEG0001,NZ_MVIA01000003.1,negative,228636-229322,100.0,85.88,,,,,2017/4/11,111.0,,
GCF_002086655.1,monacense,85693,arr-1,ARO:3002846,antibiotic inactivation,Mycolicibacterium smegmatis,rifamycin antibiotic,arr-1 is a chromosome-encoded ribosyltransferase found in Mycolicibacterium smegmatis.,GCF_002086655.1_AMRSEG0002,NZ_MVIA01000015.1,positive,48704-49092,90.05,80.72,,,,,2017/4/11,111.0,,
GCF_002086655.1,monacense,85693,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_002086655.1_AMRSEG0003,NZ_MVIA01000030.1,positive,3143-6637,99.11,81.02,,,,,2017/4/11,111.0,,
GCF_002086655.1,monacense,85693,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_002086655.1_AMRSEG0004,NZ_MVIA01000032.1,negative,34118-34449,96.23,91.27,,,,,2017/4/11,111.0,,