strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCA_000744355.1,neoaurum,1795,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCA_000744355.1_AMRSEG0001,JQLT01000001.1,positive,467675-471146,99.05,81.16,,,,,2014/8/28,191.0,,
GCA_000744355.1,neoaurum,1795,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCA_000744355.1_AMRSEG0002,JQLT01000003.1,negative,266744-267075,96.23,85.84,,,,,2014/8/28,191.0,,
GCA_000744355.1,neoaurum,1795,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCA_000744355.1_AMRSEG0003,JQLT01000012.1,positive,75446-76132,100.0,84.86,,,,,2014/8/28,191.0,,
GCA_000744355.1,neoaurum,1795,lfrA,ARO:3003967,antibiotic efflux,Mycolicibacterium smegmatis MC2 155,fluoroquinolone antibiotic,lfrA is involved in the active efflux of quinolones and is found in Mycobacteroides abscessus.,GCA_000744355.1_AMRSEG0004,JQLT01000013.1,negative,65434-66897,96.5,80.15,,,,,2014/8/28,191.0,,
GCA_001580405.1,neoaurum,1795,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCA_001580405.1_AMRSEG0001,CP011022.1,positive,1337446-1340917,99.03,81.1,,,,,2016/3/7,27.0,,
GCA_001580405.1,neoaurum,1795,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCA_001580405.1_AMRSEG0002,CP011022.1,positive,1761209-1761895,100.0,86.03,,,,,2016/3/7,27.0,,
GCA_001580405.1,neoaurum,1795,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCA_001580405.1_AMRSEG0003,CP011022.1,negative,3044161-3044492,96.23,88.55,,,,,2016/3/7,27.0,,
GCA_001580405.1,neoaurum,1795,lfrA,ARO:3003967,antibiotic efflux,Mycolicibacterium smegmatis MC2 155,fluoroquinolone antibiotic,lfrA is involved in the active efflux of quinolones and is found in Mycobacteroides abscessus.,GCA_001580405.1_AMRSEG0004,CP011022.1,positive,5353614-5355086,97.1,80.2,,,,,2016/3/7,27.0,,
SRR1587790,neoaurum,1795,lfrA,ARO:3003967,antibiotic efflux,Mycolicibacterium smegmatis MC2 155,fluoroquinolone antibiotic,lfrA is involved in the active efflux of quinolones and is found in Mycobacteroides abscessus.,SRR1587790_AMRSEG0001,NODE_13_length_162665_cov_144.739923,positive,96281-97744,96.5,80.15,,,,,,191.0,,
SRR1587790,neoaurum,1795,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR1587790_AMRSEG0002,NODE_1_length_838411_cov_141.164431,positive,169118-169449,96.23,85.84,,,,,,191.0,,
SRR1587790,neoaurum,1795,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR1587790_AMRSEG0003,NODE_2_length_723836_cov_145.673744,negative,87677-88363,100.0,84.86,,,,,,191.0,,
SRR1587790,neoaurum,1795,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR1587790_AMRSEG0004,NODE_2_length_723836_cov_145.673744,negative,557280-560751,99.05,81.16,,,,,,191.0,,
SRR5272487,neoaurum,1795,lfrA,ARO:3003967,antibiotic efflux,Mycolicibacterium smegmatis MC2 155,fluoroquinolone antibiotic,lfrA is involved in the active efflux of quinolones and is found in Mycobacteroides abscessus.,SRR5272487_AMRSEG0001,NODE_14_length_150561_cov_168.550718,negative,65558-67030,97.1,80.2,Environment,Homo sapiens,Environment:the mutant of Mycobacterium MN2,China,2014/9/1,27.0,,
SRR5272487,neoaurum,1795,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR5272487_AMRSEG0002,NODE_2_length_537276_cov_166.763165,positive,189160-192631,99.03,81.1,Environment,Homo sapiens,Environment:the mutant of Mycobacterium MN2,China,2014/9/1,27.0,,
SRR5272487,neoaurum,1795,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR5272487_AMRSEG0003,NODE_6_length_353154_cov_155.905455,negative,270983-271314,96.23,88.55,Environment,Homo sapiens,Environment:the mutant of Mycobacterium MN2,China,2014/9/1,27.0,,
SRR5272487,neoaurum,1795,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR5272487_AMRSEG0004,NODE_9_length_208334_cov_163.352886,negative,133280-133966,100.0,86.03,Environment,Homo sapiens,Environment:the mutant of Mycobacterium MN2,China,2014/9/1,27.0,,