strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name DRR161225,noviomagense,459858,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,DRR161225_AMRSEG0001,NODE_12_length_154519_cov_27.252402,negative,148411-148726,91.59,86.71,,,,,,735.0,, DRR161225,noviomagense,459858,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",DRR161225_AMRSEG0002,NODE_5_length_294588_cov_27.404118,positive,287062-290480,97.22,80.76,,,,,,735.0,, DRR161225,noviomagense,459858,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,DRR161225_AMRSEG0003,NODE_6_length_290396_cov_27.467346,negative,174894-175580,100.0,88.94,,,,,,735.0,, GCF_002086415.1,noviomagense,459858,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_002086415.1_AMRSEG0001,NZ_MVIC01000005.1,negative,160315-161001,100.0,88.94,,,,,2017/4/11,735.0,, GCF_002086415.1,noviomagense,459858,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_002086415.1_AMRSEG0002,NZ_MVIC01000012.1,positive,40194-40509,91.59,86.71,,,,,2017/4/11,735.0,, GCF_002086415.1,noviomagense,459858,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_002086415.1_AMRSEG0003,NZ_MVIC01000024.1,positive,57538-60956,97.22,80.76,,,,,2017/4/11,735.0,,