strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCF_002086815.1,parafortuitum,39692,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_002086815.1_AMRSEG0001,NZ_MVID01000006.1,negative,122783-123469,100.0,87.48,,,,,2017/4/11,656.0,,
GCF_002086815.1,parafortuitum,39692,tap,ARO:3000343,antibiotic efflux,Mycolicibacterium fortuitum,tetracycline antibiotic,"Efflux pump proteins contained within Mycobacterial genomes which confer resistance to a number of different antibiotics including aminoglycosides, and tetracyclines.",GCF_002086815.1_AMRSEG0002,NZ_MVID01000013.1,negative,41511-42701,96.83,80.27,,,,,2017/4/11,656.0,,
GCF_002086815.1,parafortuitum,39692,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_002086815.1_AMRSEG0003,NZ_MVID01000015.1,positive,7857-8158,87.54,91.39,,,,,2017/4/11,656.0,,
GCF_002086815.1,parafortuitum,39692,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_002086815.1_AMRSEG0004,NZ_MVID01000028.1,negative,35090-38569,99.0,80.79,,,,,2017/4/11,656.0,,
GCF_900417285.1,parafortuitum,39692,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_900417285.1_AMRSEG0001,NZ_UEGS01000001.1,positive,2111507-2114986,99.0,80.79,,,,,2018/7/8,656.0,,
GCF_900417285.1,parafortuitum,39692,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_900417285.1_AMRSEG0002,NZ_UEGS01000001.1,positive,2529488-2530174,100.0,87.48,,,,,2018/7/8,656.0,,
GCF_900417285.1,parafortuitum,39692,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_900417285.1_AMRSEG0003,NZ_UEGS01000001.1,positive,4644529-4644830,87.54,91.39,,,,,2018/7/8,656.0,,
GCF_900417285.1,parafortuitum,39692,tap,ARO:3000343,antibiotic efflux,Mycolicibacterium fortuitum,tetracycline antibiotic,"Efflux pump proteins contained within Mycobacterial genomes which confer resistance to a number of different antibiotics including aminoglycosides, and tetracyclines.",GCF_900417285.1_AMRSEG0004,NZ_UEGS01000001.1,positive,5523797-5524987,96.83,80.27,,,,,2018/7/8,656.0,,
GCF_900417285.1,parafortuitum,39692,APH(3')-Ia,ARO:3002641,antibiotic inactivation,Serratia marcescens,aminoglycoside antibiotic,"APH(3')-Ia is a transposon-encoded aminoglycoside phosphotransferase in E. coli and S. enterica. It is identical at the protein sequence to APH(3')-Ic, an aminoglycoside phosphotransferase encoded by plasmids, transposons and genomic islands in K. pneumoniae, A. baumannii, S. marcescens, Corynebacterium spp., Photobacterium spp. and Citrobacter spp.",GCF_900417285.1_AMRSEG0005,NZ_UEGS01000003.1,negative,500-1315,100.0,100.0,,,,,2018/7/8,656.0,,