strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
SRR6046363,paragordonae,1389713,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR6046363_AMRSEG0001,NODE_123_length_17006_cov_26.636487,negative,11264-12855,99.75,83.45,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046363,paragordonae,1389713,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR6046363_AMRSEG0002,NODE_17_length_81897_cov_30.377093,positive,16496-16827,96.23,87.35,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046363,paragordonae,1389713,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR6046363_AMRSEG0003,NODE_57_length_38492_cov_33.364308,negative,23701-27087,96.59,80.81,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046363,paragordonae,1389713,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR6046363_AMRSEG0004,NODE_74_length_30082_cov_31.218228,negative,5739-6425,100.0,90.39,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046913,paragordonae,1389713,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR6046913_AMRSEG0001,NODE_17_length_88257_cov_29.900594,negative,82515-84106,99.75,83.45,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046913,paragordonae,1389713,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR6046913_AMRSEG0002,NODE_45_length_52502_cov_29.738801,positive,16496-16827,96.23,87.65,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046913,paragordonae,1389713,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR6046913_AMRSEG0003,NODE_48_length_48905_cov_32.689898,negative,23622-27008,96.59,80.84,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR6046913,paragordonae,1389713,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR6046913_AMRSEG0004,NODE_74_length_30076_cov_30.190951,negative,5751-6437,100.0,90.68,Homo sapiens,Homo sapiens,Homo sapiens:clinical sample,United Kingdom,2016/3/31,,,
SRR8483011,paragordonae,1389713,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR8483011_AMRSEG0001,NODE_19_length_112158_cov_411.773442,positive,105709-106395,100.0,90.83,,,,Portugal,2022/9/17,869.0,,
SRR8483011,paragordonae,1389713,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR8483011_AMRSEG0002,NODE_1_length_602763_cov_348.992806,negative,192220-193811,99.75,83.45,,,,Portugal,2022/9/17,869.0,,
SRR8483011,paragordonae,1389713,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR8483011_AMRSEG0003,NODE_33_length_70602_cov_380.630233,positive,34059-34390,96.23,87.65,,,,Portugal,2022/9/17,869.0,,
SRR8483011,paragordonae,1389713,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR8483011_AMRSEG0004,NODE_6_length_349557_cov_344.380836,negative,223425-226811,96.59,81.16,,,,Portugal,2022/9/17,869.0,,
SRR8483012,paragordonae,1389713,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,SRR8483012_AMRSEG0001,NODE_21_length_120387_cov_449.798236,negative,5780-6466,100.0,90.83,,,,Portugal,2022/9/17,870.0,,
SRR8483012,paragordonae,1389713,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,SRR8483012_AMRSEG0002,NODE_2_length_410582_cov_387.243243,negative,156298-157889,99.75,83.51,,,,Portugal,2022/9/17,870.0,,
SRR8483012,paragordonae,1389713,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,SRR8483012_AMRSEG0003,NODE_36_length_73771_cov_339.194524,positive,37253-37584,96.23,87.65,,,,Portugal,2022/9/17,870.0,,
SRR8483012,paragordonae,1389713,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",SRR8483012_AMRSEG0004,NODE_5_length_332834_cov_386.561155,negative,273351-276737,96.59,81.16,,,,Portugal,2022/9/17,870.0,,
SRR8483012,paragordonae,1389713,tet(K),ARO:3000178,antibiotic efflux,Staphylococcus aureus,tetracycline antibiotic,"TetK is a tetracycline efflux protein found in both Gram-negative (Haemophilus and Gallibacterium) and Gram-positive (many species, including mycobacteria) bacteria.",SRR8483012_AMRSEG0005,NODE_85_length_2228_cov_3.082679,negative,1-1236,89.57,99.92,,,,Portugal,2022/9/17,870.0,,