strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name ERR1363612,pseudoshottsii,265949,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",ERR1363612_AMRSEG0001,NODE_112_length_13549_cov_47.303871,positive,3391-6809,97.13,80.81,,,,,,,, ERR1363612,pseudoshottsii,265949,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,ERR1363612_AMRSEG0002,NODE_3_length_129363_cov_51.148368,negative,54331-54645,91.3,84.13,,,,,,,, ERR1363612,pseudoshottsii,265949,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,ERR1363612_AMRSEG0003,NODE_59_length_33649_cov_51.118799,positive,19220-19765,99.82,82.08,,,,,,,, ERR1363612,pseudoshottsii,265949,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,ERR1363612_AMRSEG0004,NODE_72_length_26107_cov_50.734565,negative,12091-13683,99.94,84.75,,,,,,,, ERR1363612,pseudoshottsii,265949,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,ERR1363612_AMRSEG0005,NODE_94_length_16822_cov_51.017841,negative,13189-13875,100.0,90.54,,,,,,,, ERR1363613,pseudoshottsii,265949,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",ERR1363613_AMRSEG0001,NODE_114_length_13549_cov_48.758045,positive,3391-6809,97.13,80.81,,,,,,,, ERR1363613,pseudoshottsii,265949,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,ERR1363613_AMRSEG0002,NODE_3_length_129498_cov_51.638931,positive,74719-75033,91.3,84.13,,,,,,,, ERR1363613,pseudoshottsii,265949,AAC(2')-Ic,ARO:3002525,antibiotic inactivation,Mycobacterium tuberculosis H37Rv,aminoglycoside antibiotic,AAC(2')-Ic is a chromosomal-encoded aminoglycoside acetyltransferase in M. tuberculosis and Mycobacterium tuberculosis variant bovis.,ERR1363613_AMRSEG0003,NODE_60_length_33650_cov_51.637330,positive,19221-19766,99.82,82.08,,,,,,,, ERR1363613,pseudoshottsii,265949,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,ERR1363613_AMRSEG0004,NODE_72_length_26107_cov_50.790854,negative,12091-13683,99.94,84.75,,,,,,,, ERR1363613,pseudoshottsii,265949,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,ERR1363613_AMRSEG0005,NODE_96_length_16821_cov_52.119585,negative,13188-13874,100.0,90.54,,,,,,,,