strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name DRR161205,saskatchewanense,220927,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,DRR161205_AMRSEG0001,NODE_10_length_221228_cov_18.345516,negative,54693-55379,100.0,89.52,,,,,,691.0,, DRR161205,saskatchewanense,220927,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",DRR161205_AMRSEG0002,NODE_17_length_120617_cov_18.350606,positive,65192-68578,96.59,81.84,,,,,,691.0,, DRR161205,saskatchewanense,220927,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,DRR161205_AMRSEG0003,NODE_41_length_17736_cov_18.622192,positive,1738-2069,96.23,86.45,,,,,,691.0,, DRR161205,saskatchewanense,220927,efpA,ARO:3003955,antibiotic efflux,Mycobacterium tuberculosis H37Rv,rifamycin antibiotic;isoniazid-like antibiotic,efpA is an MFS transporter found in Mycobacterium tuberculosis.,DRR161205_AMRSEG0004,NODE_6_length_315067_cov_18.170080,negative,137086-138677,99.87,84.18,,,,,,691.0,,