strain_accession,species_name,species_id,gene_name,card_accession,mechanism,AMR_gene_ref_strain,card_drug_class,definition,amr_seqid,contig,strand,position,coverage,identity,host,source,source_detail,country,date,MLST,subspecies_id,subspecies_name
GCA_001695755.1,tokaiense,39695,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCA_001695755.1_AMRSEG0001,CP016640.1,positive,1500378-1503772,96.5,81.81,,,,,2016/7/28,517.0,,
GCA_001695755.1,tokaiense,39695,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCA_001695755.1_AMRSEG0002,CP016640.1,positive,1911769-1912455,100.0,85.15,,,,,2016/7/28,517.0,,
GCA_001695755.1,tokaiense,39695,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCA_001695755.1_AMRSEG0003,CP016640.1,positive,3800158-3800489,96.23,87.35,,,,,2016/7/28,517.0,,
GCA_001695755.1,tokaiense,39695,arr-1,ARO:3002846,antibiotic inactivation,Mycolicibacterium smegmatis,rifamycin antibiotic,arr-1 is a chromosome-encoded ribosyltransferase found in Mycolicibacterium smegmatis.,GCA_001695755.1_AMRSEG0004,CP016640.1,negative,3849945-3850304,83.33,80.28,,,,,2016/7/28,517.0,,
GCF_900453365.1,tokaiense,39695,mtrA,ARO:3000816,antibiotic efflux,Mycobacterium tuberculosis H37Rv,penam;macrolide antibiotic,MtrA is a transcriptional activator of the MtrCDE multidrug efflux pump of Neisseria gonorrhoeae.,GCF_900453365.1_AMRSEG0001,NZ_UGQT01000001.1,negative,1229880-1230566,100.0,84.57,,,,,2018/8/1,817.0,,
GCF_900453365.1,tokaiense,39695,rpoB2,ARO:3000501,antibiotic target alteration,Nocardia farcinica IFM 10152,rifamycin antibiotic,"Due to gene duplication, the genomes of Nocardia species include both rifampin-sensitive beta-subunit of RNA polymerase (rpoB) and rifampin-resistant beta-subunit of RNA polymerase (rpoB2) genes, with ~88% similarity between the two gene products. Expression of the rpoB2 variant results in replacement of rifampin sensitivity with rifampin resistance.",GCF_900453365.1_AMRSEG0002,NZ_UGQT01000001.1,negative,1615409-1618803,96.5,81.86,,,,,2018/8/1,817.0,,
GCF_900453365.1,tokaiense,39695,RbpA,ARO:3000245,antibiotic target protection,Mycolicibacterium smegmatis MC2 155,rifamycin antibiotic,RNA-polymerase binding protein which confers resistance to rifampin.,GCF_900453365.1_AMRSEG0003,NZ_UGQT01000001.1,negative,5711422-5711753,96.23,88.86,,,,,2018/8/1,817.0,,